Use the renal measure and units named by this source. Confirm product, indication, age, stable versus changing kidney function, and exact dialysis modality. The selected summary is not a complete prescribing monograph. Renal method and dosing checklist
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1 additional source qualifications - review before use
Adults or adolescents with HIV taking the doravirine/lamivudine/TDF fixed-dose tablet.
Renal measure
Adult CrCl in mL/min; panel has a separate hemodialysis entry.
Source revision
Online guidance checked 2026-11-07; section revision not established.
Retrieved
2026-11-07 (not the revision date)
Restriction or avoidance guidance. Read the specific threshold, age, formulation and dialysis exclusions; do not generalize across products.
Appendix B, doravirine/lamivudine/TDF row
The panel advises avoiding TDF when possible below CrCl 60 mL/min. This doravirine/lamivudine/TDF fixed combination is not recommended below 50 mL/min or on HD. The ingredient-level TDF interval must not be applied to the fixed tablet.
Source revision: Online guidance checked 2026-11-07; section revision not established. | Retrieved: 2026-11-07. Retrieval date is not the revision date.
All sources, comparison tools and evidence navigation
Source-first renal review
Evidence sources and renal implications
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Renal-context checklist: population, kidney trend and dialysis
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These are specific issues found during source review, not an automated judgment that one source is universally correct. A label mirror and its original label are not independent evidence.
Source scope / renal recommendation differences
Delstrigo - product and source limitations
Verify all three ingredients. Doravirine alone has different renal guidance.
How to use this: Apply only to the stated formulation, indication and renal population.
Choose a source, then jump to its renal or dialysis section. These links locate stored text; they do not merge regimens or certify that sources agree.
Independent clinical review is pending. These selected summaries are not an approved institutional dosing protocol. Confirm the exact product, the complete current source and local policy before use.
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Compare or copy source versions
All content below is stored locally. Read a whole source version; do not combine its dose with another source's interval, renal metric or dialysis assumptions.
Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Below estimated CrCl 50 mL/min, the fixed-dose tablet is not recommended because the lamivudine and TDF doses cannot be lowered individually. Verify all three ingredients. Doravirine alone has different renal guidance.
RDM73-delstrigo-official-1 · Source locator: Renal guidance: 2 and 8.6
Renal method: Use the renal measure explicitly present in the RX passage. Source date: Mirror revision not established in the reviewed passage. Retrieved: 2026-11-07
Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Restriction or avoidance guidance. Read the specific threshold, age, formulation and dialysis exclusions; do not generalize across products.
HHS HIV guidelines panel / ClinicalInfo · Adults or adolescents with HIV taking the doravirine/lamivudine/TDF fixed-dose tablet.
Renal method: Adult CrCl in mL/min; panel has a separate hemodialysis entry. Source date: Online guidance checked 2026-11-07; section revision not established. Retrieved: 2026-11-07
Restriction or avoidance guidance. Read the specific threshold, age, formulation and dialysis exclusions; do not generalize across products.
The panel advises avoiding TDF when possible below CrCl 60 mL/min. This doravirine/lamivudine/TDF fixed combination is not recommended below 50 mL/min or on HD. The ingredient-level TDF interval must not be applied to the fixed tablet.
Additional summaries stored on this page: 1 official-label, 1 RX List, 1 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.
This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.
