Original GlobalRPh source
- Product / population
- Preserved GlobalRPh source, not a freshly verified product label
- Renal measure
- Use the method specified in the original source
Historical source: not automatically current. Review current official labeling and separately attributed additions before use.
Usual Dosing (Adults)
1 to 2 g IV/IM every 8 to 12 hours. Life-threatening: 3 to 4 g IV every 8 hours or 2 g every 4 hours; maximum 12 g/day.
Renal Dosing
| CrCl (mL/min) | Dose |
|---|---|
| >79 | No change |
| 50 to 79 | 500 mg to 1.5 g every 8 hours |
| 5 to 49 | 250 mg to 1 g every 12 hours |
| 0 to 4 or dialysis | 250 to 500 mg every 24 hours or 500 mg to 1 g every 48 hours |
Hemodialysis
Use the 0 to 4 mL/min schedule and give after hemodialysis. Peritoneal dialysis: 500 mg to 1 g every 24 hours.