Baricitinib tablets (Olumiant, adults) - selected U.S. label sections
- Product / population
- Adult OLUMIANT oral tablets. The indications below must not be combined.
- Renal measure
- eGFR in mL/min/1.73 m2; indication-specific tables
Selected renal sections only, not a complete monograph. Exact product, indication, patient population, renal method and all other contraindications/interactions remain controlling.
Second independent renal reference and clinician adjudication remain pending; no all-indication, dialysis or pediatric dose may be inferred from an omitted field.
Rheumatoid arthritis - renal dose
| eGFR | Oral dose |
|---|---|
| 60 to below 90 | 2 mg once daily |
| 30 to below 60 | 1 mg once daily |
| Below 30 | Not recommended |
Alopecia areata - renal dose
At eGFR 30 to below 60, reduce a 2 mg daily regimen to 1 mg daily, or a 4 mg daily regimen to 2 mg daily. Below 30, use is not recommended.
COVID-19 - adult renal dose
| eGFR | Oral dose |
|---|---|
| 60 to below 90 | 4 mg once daily |
| 30 to below 60 | 2 mg once daily |
| 15 to below 30 | 1 mg once daily |
| Below 15, dialysis, end-stage disease or acute kidney injury | Not recommended |
Review the separate indication, treatment-duration and drug-interaction instructions.
Source: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=866e9f35-9035-4581-a4b1-75a621ab55cf