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Clinical context remains essential
Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.
This qualitative statement remains a full source-specific protocol page. It is oral fosfomycin, not an IV protocol.
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UCSF oral fosfomycin - cystitis schedules
Product / population
Adult oral fosfomycin; complicated-cystitis repeated dosing is an institutional off-label use relative to MONUROL labeling.
Renal method
CrCl >50 versus <50 mL/min as printed; exactly 50 is not assigned.
Source revision
Source revision date not established in selected retrieval.
Retrieved
2026-09-07
Local review status
Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.
Documented differences and cautions on this drug
All record notes are retained here, including notes about sources not selected in this review.
Labeled single-dose cystitis versus repeated institutional dosing
MONUROL labeling is limited to uncomplicated cystitis. UCSF separately supplies repeated oral doses for complicated cystitis and leaves CrCl exactly 50 unassigned between >50 and <50.
What to reconcile: Document the institutional/off-label rationale and exact renal band. Do not use these oral schedules for pyelonephritis or IV CONTEPO.
UCSF Infectious Diseases Management Program · Adult oral fosfomycin; complicated-cystitis repeated dosing is an institutional off-label use relative to MONUROL labeling.
Renal method: CrCl >50 versus <50 mL/min as printed; exactly 50 is not assigned. Source date: Source revision date not established in selected retrieval. Retrieved: 2026-09-07
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.
Renal dosing, restrictions and evidence limits
Uncomplicated cystitis: 3 g orally once in both printed renal bands. Complicated cystitis: 3 g every two days for three doses at CrCl >50, or every three days for three doses at CrCl <50. The page leaves exactly 50 unspecified; clarify that boundary.
Intermittent HD: uncomplicated cystitis 3 g once after HD; complicated cystitis 3 g every three days for three doses, after HD. Continuous-HD data are absent. These oral schedules are not treatment instructions for pyelonephritis or IV CONTEPO.
RDM41-professional-fosfomycin-c33511c96a-C1 · Source locator: Adult nondialysis and dialysis tables
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
GlobalRPh v6.6 | RDM66-DIRECT-PHP-20260911 | Local library date 2026-09-11. Selected-card identity does not imply clinical verification.