GlobalRPh Renal Dosing Masterv7.4
Renal Dosing Master: fast drug lookup
Source review / handoff

Daptomycin (Dapzura RT), IV injection

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

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Dapzura RT - labeled renal guidance

Product / population
Daptomycin (Dapzura RT), IV injection
Renal method
Creatinine clearance (CrCl), mL/min
Source revision
DailyMed SPL version 7, posted May 21, 2026
Retrieved
2026-11-07
Local review status
Selected renal passages reviewed; independent clinician adjudication pending.

Documented differences and cautions on this drug

All record notes are retained here, including notes about sources not selected in this review.

Dapzura RT - product and source limitations

At CrCl at least 30 the usual interval is 24 hours. Monitor renal function and CPK more frequently in renal impairment.

What to reconcile: Apply only to the stated formulation, indication and renal population.

Selected renal passages reviewed; independent clinician adjudication pending.

Open this note and its source references
Official

Dapzura RT - labeled renal guidance

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DailyMed / product prescribing information · Daptomycin (Dapzura RT), IV injection

Renal method: Creatinine clearance (CrCl), mL/min
Source date: DailyMed SPL version 7, posted May 21, 2026
Retrieved: 2026-11-07

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Selected renal passages reviewed; independent clinician adjudication pending.

Renal guidance: 2.6 Dosage in Patients with Renal Impairment / 5.10 Decreased Efficacy in Patients with Moderate Baseline Renal Impairment / 8.6 Patients with Renal Impairment

For adults at CrCl below 30 mL/min, including HD or CAPD, give the indication-specific dose every 48 hours: 4 mg/kg for complicated skin infection or 6 mg/kg for S. aureus bacteremia. Dose after HD when feasible. At CrCl at least 30 the usual interval is 24 hours. Monitor renal function and CPK more frequently in renal impairment.

RDM74-dapzura-rt-official-1 · Source locator: Renal guidance: 2.6 Dosage in Patients with Renal Impairment / 5.10 Decreased Efficacy in Patients with Moderate Baseline Renal Impairment / 8.6 Patients with Renal Impairment

Source identity and provenance
Source family
product_label
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=cb1283e1-35b8-425c-b338-d9ac0c7161f8
Retrieved
2026-11-07
Renal-function method
Creatinine clearance (CrCl), mL/min
Source date/version
DailyMed SPL version 7, posted May 21, 2026
Hash meaning
SHA-256 of the local selected-source summary
Local summary SHA-256
6c72b6064f685b1d7a4ebab6c4a6d3c24d16500bb77dfca3a3c5021ed09b01ce

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=rx-dapzura-rt&s1=RDM74-dapzura-rt-official&h1=f989fad4c8eb629f60662073cfe719e0ffb89783da94d5da39793fa5545eac21

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