Use the renal measure and units named by this source. Confirm product, indication, age, stable versus changing kidney function, and exact dialysis modality. The selected summary is not a complete prescribing monograph. Renal method and dosing checklist
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1 additional source qualifications - review before use
At CrCl at least 30 the usual interval is 24 hours. Monitor renal function and CPK more frequently in renal impairment.
Before applying: Apply only to the stated formulation, indication and renal population.
Also check: Dapzura RT - product and source limitations
Official source
Dapzura RT - labeled renal guidance
Renal action and limits
Daptomycin (Dapzura RT), IV injection Creatinine clearance (CrCl), mL/min
Action or finding
For adults at CrCl below 30 mL/min, including HD or CAPD, give the indication-specific dose every 48 hours: 4 mg/kg for complicated skin infection or 6 mg/kg for S. aureus bacteremia. Dose after HD when feasible.
Limits and monitoring
At CrCl at least 30 the usual interval is 24 hours. Monitor renal function and CPK more frequently in renal impairment.
Before use
Apply only to the stated formulation, indication and renal population.
DailyMed SPL version 7, posted May 21, 2026 | Selected sections checked 2026-11-07. Independent clinical review pending.
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
Renal guidance: 2.6 Dosage in Patients with Renal Impairment / 5.10 Decreased Efficacy in Patients with Moderate Baseline Renal Impairment / 8.6 Patients with Renal Impairment
For adults at CrCl below 30 mL/min, including HD or CAPD, give the indication-specific dose every 48 hours: 4 mg/kg for complicated skin infection or 6 mg/kg for S. aureus bacteremia. Dose after HD when feasible. At CrCl at least 30 the usual interval is 24 hours. Monitor renal function and CPK more frequently in renal impairment.
Source revision: DailyMed SPL version 7, posted May 21, 2026 | Retrieved: 2026-11-07. Retrieval date is not the revision date.
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Renal-context checklist: population, kidney trend and dialysis
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Source scope / renal recommendation differences
Dapzura RT - product and source limitations
At CrCl at least 30 the usual interval is 24 hours. Monitor renal function and CPK more frequently in renal impairment.
How to use this: Apply only to the stated formulation, indication and renal population.
Choose a source, then jump to its renal or dialysis section. These links locate stored text; they do not merge regimens or certify that sources agree.
Independent clinical review is pending. These selected summaries are not an approved institutional dosing protocol. Confirm the exact product, the complete current source and local policy before use.
No dialysis or renal heading shown? Read the complete source summary. Absence of a heading is not evidence that dose adjustment is unnecessary.
Compare or copy source versions
All content below is stored locally. Read a whole source version; do not combine its dose with another source's interval, renal metric or dialysis assumptions.
Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Renal guidance: 2.6 Dosage in Patients with Renal Impairment / 5.10 Decreased Efficacy in Patients with Moderate Baseline Renal Impairment / 8.6 Patients with Renal Impairment
For adults at CrCl below 30 mL/min, including HD or CAPD, give the indication-specific dose every 48 hours: 4 mg/kg for complicated skin infection or 6 mg/kg for S. aureus bacteremia. Dose after HD when feasible. At CrCl at least 30 the usual interval is 24 hours. Monitor renal function and CPK more frequently in renal impairment.
RDM74-dapzura-rt-official-1 · Source locator: Renal guidance: 2.6 Dosage in Patients with Renal Impairment / 5.10 Decreased Efficacy in Patients with Moderate Baseline Renal Impairment / 8.6 Patients with Renal Impairment
GlobalRPh RX List / product-label mirror · Daptomycin (Dapzura RT), IV injection
Renal method: Use the renal measure explicitly present in the RX passage. Source date: Mirror revision not established in the reviewed passage. Retrieved: 2026-11-07
Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
Additional summaries stored on this page: 1 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.
This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.
