GlobalRPh Renal Dosing Masterv6.6
Source review / handoff

Amoxicillin/Clav

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

The source summary mentions an after-dialysis dose; the source package-insert paragraph says both during and at the end of dialysis. Both statements are retained and require product-specific reconciliation.

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UCSF - amoxicillin/clavulanate: standard and bloodstream-infection regimens

Product / population
Adults; oral immediate-release amoxicillin/clavulanate. Separate indication-specific institutional schedules.
Renal method
CrCl in mL/min where specified; no equation inferred.
Source revision
Revision date not stated in the reviewed page.
Retrieved
2026-09-05
Local review status
Locally included source-specific summary. Regimen differences are not automatically resolved.

Documented differences and cautions on this drug

All record notes are retained here, including notes about sources not selected in this review.

Conventional AUGMENTIN is not XR or ES-600

The conventional renal table cannot be transferred to XR, and clavulanate content differs among formulations.

What to reconcile: Match both component strengths and formulation before using any table.

Source-specific interpretation; independent clinician adjudication pending.

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Professional

UCSF - amoxicillin/clavulanate: standard and bloodstream-infection regimens

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UCSF Infectious Diseases Management Program · Adults; oral immediate-release amoxicillin/clavulanate. Separate indication-specific institutional schedules.

Renal method: CrCl in mL/min where specified; no equation inferred.
Source date: Revision date not stated in the reviewed page.
Retrieved: 2026-09-05

Locally included source-specific summary. Regimen differences are not automatically resolved.

Dosing / renal protocol and limits

Most indications: CrCl >30 mL/min, 875/125 mg orally twice daily; 10-29, 500/125 mg twice daily; <10, 500/125 mg daily. Intermittent HD: 500/125 mg initially then each evening; continuous HD: 500/125 mg twice daily.

The institution's separate Gram-negative bloodstream-infection regimen uses 875/125 mg three times daily at CrCl >30, twice daily at 10-29, and daily below 10. Its HD regimen is 875/125 mg initially then each evening; continuous HD uses that strength three times daily.

The 875-mg renal strategy for bloodstream infection is not interchangeable with standard U.S. product-label renal restrictions. Keep it under the named institutional indication. Exactly 30 is omitted in the source ranges.

RDM30-055-amoxicillinclav-1 · Source locator: UCSF - amoxicillin/clavulanate: standard and bloodstream-infection regimens; renal/dosing sections and stated qualifiers

Source identity and provenance
Source
https://idmp.ucsf.edu/content/amoxicillin-clavulanate
Retrieved
2026-09-05
Renal-function method
CrCl in mL/min where specified; no equation inferred.
Source date/version
Revision date not stated in the reviewed page.
Hash meaning
Locally authored summary text; not original SPL, HTML or PDF bytes
Local summary SHA-256
ff118685a2a2e07b66036ff154c6f5ba9c83baf0d460f4ca4c4f1458879ca7f3

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh v6.6 | RDM66-DIRECT-PHP-20260911 | Local library date 2026-09-11. Selected-card identity does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=amoxicillinclav&s1=RDM30-055-amoxicillinclav&h1=dfc478666e25e93f07bfe63db5e2eb4be4f61b481647560ea2a9ee440b467c43