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Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.
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Renal Drug Handbook, 5th edition - Isavuconazole (administered as isavuconazonium sulfate)
Product / population
Historical adult renal/RRT summary. U.S. product identity anchored to the separate locally included DailyMed label. This is not a current U.S. product label.
Renal method
Book table headed GFR (mL/min); its preface states renal adjustments generally derive from Cockcroft-Gault CrCl. Do not silently relabel as indexed eGFR.
Source revision
5th edition; 2019 copyright; historical reference
Retrieved
2026-09-05
Local review status
Historical handbook cross-check; not a current U.S. protocol
Handbook
Renal Drug Handbook, 5th edition - Isavuconazole (administered as isavuconazonium sulfate)
UK Renal Pharmacy Group / CRC Press · Historical adult renal/RRT summary. U.S. product identity anchored to the separate locally included DailyMed label. This is not a current U.S. product label.
Renal method: Book table headed GFR (mL/min); its preface states renal adjustments generally derive from Cockcroft-Gault CrCl. Do not silently relabel as indexed eGFR. Source date: 5th edition; 2019 copyright; historical reference Retrieved: 2026-09-05
Historical handbook cross-check; not a current U.S. protocol
Historical renal / replacement-therapy guidance
The 20-50, 10-20 and <10 mL/min bands retain the usual indication-specific dose. PD, HD, high-flux and continuous therapy also retain usual doses; the book describes no dialytic removal. Its dose is expressed as 200 mg active isavuconazole every 8 hours for six doses then daily, beginning 12-24 hours after the final load. The U.S. CRESEMBA section expresses the equivalent as 372 mg prodrug. Do not confuse the masses.
HB30-isavuconazonium-1 · Source locator: Printed page 542: renal impairment, RRT and other information
Source-specific limits
Separate source recommendation, not proof of agreement or contemporary clinical validation. Dialysis predictions are retained with their original certainty.
Source identity and provenance
Retrieved
2026-09-05
Handbook page
5th edition, printed p. 542; uploaded PDF p. 561
Renal-function method
Book table headed GFR (mL/min); its preface states renal adjustments generally derive from Cockcroft-Gault CrCl. Do not silently relabel as indexed eGFR.
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
GlobalRPh v6.6 | RDM66-DIRECT-PHP-20260911 | Local library date 2026-09-11. Selected-card identity does not imply clinical verification.