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UCSF - ceftaroline: standard and severe-infection schedules
Product / population
Adults; source-specific institutional guidance. Match route, indication and renal replacement modality.
Renal method
CrCl in mL/min where specified; no equation inferred.
Source revision
Revision date not stated in the reviewed page.
Retrieved
2026-09-05
Local review status
Locally included source-specific summary. Regimen differences are not automatically resolved.
Professional
UCSF - ceftaroline: standard and severe-infection schedules
UCSF Infectious Diseases Management Program · Adults; source-specific institutional guidance. Match route, indication and renal replacement modality.
Renal method: CrCl in mL/min where specified; no equation inferred. Source date: Revision date not stated in the reviewed page. Retrieved: 2026-09-05
Locally included source-specific summary. Regimen differences are not automatically resolved.
Dosing / renal protocol and limits
Limits that apply to these rows
Printed bands overlap at 30. Higher-frequency dosing is institutional. Some serious infections with CrCl <50 or IHD may instead use every-12-hour dosing after ID pharmacy review.
Skin infection or CAP with low MRSA risk - IV
CrCl, mL/min
Source-specific dose / instruction
>50
600 mg every 12 hours
30-50
400 mg every 12 hours
15-30
300 mg every 12 hours
<15
200 mg every 12 hours
Severe infection / suspected or documented MRSA pneumonia - IV
CrCl, mL/min
Source-specific dose / instruction
>50
600 mg every 8 hours
30-50
400 mg every 8 hours
15-30
300 mg every 8 hours
<15
200 mg every 8 hours
Dialysis guidance - separate source-specific schedules
Ceftaroline - dialysis
Dialysis setting / indication
Source-specific schedule
IHD - first indication group
200 mg every 12 hours
IHD - severe infection
200 mg every 8 hours
Continuous HD - first indication group
400 mg every 12 hours
Continuous HD - severe infection
600 mg every 12 hours
Read the retained text before reformatting
CrCl bands >50 / 30-50 / 15-30 / <15 mL/min correspond to IV doses 600 / 400 / 300 / 200 mg. For skin infection or community-acquired pneumonia with low MRSA risk, give every 12 hours. For severe infection or pneumonia with suspected/documented MRSA, this institutional regimen uses every 8 hours. The source overlaps at 30.
Intermittent HD: 200 mg every 12 hours for the first group or every 8 hours for severe infection. Continuous HD: 400 mg every 12 hours for the first group or 600 mg every 12 hours for severe infection. Some serious infections with CrCl <50 or IHD may use every-12-hour dosing after ID pharmacy review. The higher-frequency strategy is source-specific.
RDM30-041-ceftaroline-1 · Source locator: UCSF - ceftaroline: standard and severe-infection schedules; renal/dosing sections and stated qualifiers
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
GlobalRPh v6.6 | RDM66-DIRECT-PHP-20260911 | Local library date 2026-09-11. Selected-card identity does not imply clinical verification.