GlobalRPh Renal Dosing Masterv7.4
Renal Dosing Master: fast drug lookup
Source review / handoff

Hydroxyurea capsules (Hydrea, oncology)

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

Selecting here opens the current stored cards. The pinned link below records their fingerprints. Do not enter patient information in links or searches.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

Check source scope before reading a dose

Hydrea - labeled renal guidance

Product / population
Hydroxyurea (Hydrea), oral capsule
Renal method
Measured creatinine clearance, mL/min
Source revision
DailyMed SPL version 21, posted Jan 28, 2026
Retrieved
2026-11-07
Local review status
Selected renal passages reviewed; independent clinician adjudication pending.

Documented differences and cautions on this drug

All record notes are retained here, including notes about sources not selected in this review.

Hydrea - product and source limitations

Monitor blood counts closely. Confirm Hydrea and its labeled indication before applying the regimen.

What to reconcile: Apply only to the stated formulation, indication and renal population.

Selected renal passages reviewed; independent clinician adjudication pending.

Open this note and its source references
Official

Hydrea - labeled renal guidance

Open original reference

DailyMed / product prescribing information · Hydroxyurea (Hydrea), oral capsule

Renal method: Measured creatinine clearance, mL/min
Source date: DailyMed SPL version 21, posted Jan 28, 2026
Retrieved: 2026-11-07

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Selected renal passages reviewed; independent clinician adjudication pending.

Renal guidance: 2.3 Dose Modifications for Renal Impairment / 8.6 Renal Impairment / Renal Impairment

At measured CrCl below 60 mL/min or in ESRD, reduce the initial once-daily dose from 15 to 7.5 mg/kg. Give after hemodialysis on dialysis days. Monitor blood counts closely. Confirm Hydrea and its labeled indication before applying the regimen.

RDM74-hydrea-official-1 · Source locator: Renal guidance: 2.3 Dose Modifications for Renal Impairment / 8.6 Renal Impairment / Renal Impairment

Source identity and provenance
Source family
product_label
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6053c775-68de-45e4-9af9-33b18fd0e140
Retrieved
2026-11-07
Renal-function method
Measured creatinine clearance, mL/min
Source date/version
DailyMed SPL version 21, posted Jan 28, 2026
Hash meaning
SHA-256 of the local selected-source summary
Local summary SHA-256
0f7359cf8b8adb283cf84417395b743d8f4df9989af61e96dcb05b1d78f80dea

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=hydroxyurea-hydrea&s1=RDM74-hydrea-official&h1=c72d95a3493b8b0b6daa7842d22ab1e4749d8c1b6a988cfb259ec18e927364d2

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