GlobalRPh Renal Dosing Masterv6.6
Source review / handoff

Fosfomycin - oral

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

Selecting here opens the current stored cards. The pinned link below records their fingerprints. Do not enter patient information in links or searches.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

This qualitative statement remains a full source-specific protocol page. It is oral fosfomycin, not an IV protocol.

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GlobalRPh RX List - MONUROL

Product / population
Oral fosfomycin for labeled uncomplicated cystitis in women; not IV fosfomycin.
Renal method
Renal PK observations include CrCl 7-54 mL/min; no renal interval table in the selected label.
Source revision
Source revision date not established in selected retrieval.
Retrieved
2026-09-07
Local review status
Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Documented differences and cautions on this drug

All record notes are retained here, including notes about sources not selected in this review.

Labeled single-dose cystitis versus repeated institutional dosing

MONUROL labeling is limited to uncomplicated cystitis. UCSF separately supplies repeated oral doses for complicated cystitis and leaves CrCl exactly 50 unassigned between >50 and <50.

What to reconcile: Document the institutional/off-label rationale and exact renal band. Do not use these oral schedules for pyelonephritis or IV CONTEPO.

Source-specific interpretation; independent clinician adjudication pending.

Open this note and its source references
Rxlist

GlobalRPh RX List - MONUROL

Open original reference

GlobalRPh-hosted RX List · Oral fosfomycin for labeled uncomplicated cystitis in women; not IV fosfomycin.

Renal method: Renal PK observations include CrCl 7-54 mL/min; no renal interval table in the selected label.
Source date: Source revision date not established in selected retrieval.
Retrieved: 2026-09-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

The labeled regimen is a single 3 g oral dose for uncomplicated cystitis; not pyelonephritis or perinephric abscess. Declining renal function prolonged elimination and reduced urinary recovery. The renal PK paragraph does not establish a repeated-dose schedule for complicated infection. Keep separately attributed institutional off-label schedules distinct from the label.

RDM41-rxlist-fosfomycin-a9090b9e08-C1 · Source locator: Indications, Dosage and Clinical Pharmacology / Renal Insufficiency

Source identity and provenance
Source family
product_label_mirror
Source
https://globalrph.com/rx-list/monurol-drug/
Retrieved
2026-09-07
Renal-function method
Renal PK observations include CrCl 7-54 mL/min; no renal interval table in the selected label.
Source date/version
Source revision date not established in selected retrieval.
Hash meaning
SHA-256 of local authored summary only; not original HTML, PDF or SPL bytes.
Local summary SHA-256
a80e8db1a21fa56e450c85f5bf18859d3769e2a2da4c29665fa99818c2f08972

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh v6.6 | RDM66-DIRECT-PHP-20260911 | Local library date 2026-09-11. Selected-card identity does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=fosfomycin&s1=RDM41-rxlist-fosfomycin-a9090b9e08&h1=b21b5875d34e119b9a0a0f018635cb16d03602cd229c125a8e44375b616a8574