GlobalRPh Renal Dosing Masterv6.6
Source review / handoff

Emtricitabine/tenofovir disoproxil fumarate (Truvada)

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

Selecting here opens the current stored cards. The pinned link below records their fingerprints. Do not enter patient information in links or searches.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

Historical treatment-oriented fixed-combination table. Do not apply this renal interval to HIV PrEP or to tenofovir alafenamide combinations.

Check source scope before reading a dose

NIH adult ARV table: Emtricitabine/TDF

Product / population
Adults with HIV; product-specific renal recommendations.
Renal method
CrCl (mL/min), usually Cockcroft-Gault.
Source revision
Not established
Retrieved
2026-09-05
Local review status
Source-read local summary; source-specific recommendations are not automatically interchangeable.

Documented differences and cautions on this drug

All record notes are retained here, including notes about sources not selected in this review.

TRUVADA: treatment interval reduction is not a PrEP strategy

The selected product source has different renal restrictions for treatment and prevention. Its treatment table also identifies ideal (lean) body weight.

What to reconcile: Confirm indication and source-defined clearance method before selecting an interval; do not transfer the treatment-only reduced-frequency regimen to PrEP.

Source-specific interpretation; independent clinician adjudication pending.

Open this note and its source references
Professional

NIH adult ARV table: Emtricitabine/TDF

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NIH ClinicalInfo HIV guidelines · Adults with HIV; product-specific renal recommendations.

Renal method: CrCl (mL/min), usually Cockcroft-Gault.
Source date: Not established
Retrieved: 2026-09-05

Source-read local summary; source-specific recommendations are not automatically interchangeable.

NIH dose and renal statement

HIV treatment: one tablet daily; CrCl 30-49: every 48 hours; <30 or HD: not recommended. This is not PrEP guidance.

truvada:nih-arv-truvada-1 · Source locator: Appendix B: Emtricitabine/TDF row

Source identity and provenance
Source
https://clinicalinfo.hiv.gov/en/guidelines/hiv-clinical-guidelines-adult-and-adolescent-arv/drug-characteristics-tables-renal-hepatic-insufficiency-full
Retrieved
2026-09-05
Renal-function method
CrCl (mL/min), usually Cockcroft-Gault.
Hash meaning
Locally authored source summary, not original SPL/XML/PDF bytes
Local summary SHA-256
c5f8ca9aa4b655fb46798d09e4d2bcd305198975570fdfe2dc6e2d0cebabe158

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh v6.6 | RDM66-DIRECT-PHP-20260911 | Local library date 2026-09-11. Selected-card identity does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=truvada&s1=nih-arv-truvada&h1=86e54790af4e0b6d67fb0dde40ced31d931787165fb70d345fb36347334b5b85