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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.
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Clinical context remains essential
Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.
The manufacturer-derived and alternative historical strategies are separate source regimens, not interchangeable defaults.
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UCSF - ciprofloxacin
Product / population
Adults; systemic oral or IV ciprofloxacin, not otic/ophthalmic products.
Renal method
CrCl in mL/min where specified; no equation inferred.
Source revision
Revision date not stated in the reviewed page.
Retrieved
2026-09-05
Local review status
Locally included source-specific summary. Regimen differences are not automatically resolved.
UCSF Infectious Diseases Management Program · Adults; systemic oral or IV ciprofloxacin, not otic/ophthalmic products.
Renal method: CrCl in mL/min where specified; no equation inferred. Source date: Revision date not stated in the reviewed page. Retrieved: 2026-09-05
Locally included source-specific summary. Regimen differences are not automatically resolved.
Dosing / renal protocol and limits
Standard treatment at CrCl >=30 mL/min uses either 400 mg IV every 12 hours or 500 mg orally twice daily. Below 30, use either 400 mg IV daily or 500 mg orally daily.
For Pseudomonas, Gram-negative bacteremia or induction of staphylococcal hardware infection, CrCl >50 uses 400 mg IV every 8 hours or 750 mg orally every 12 hours; CrCl 30-50 uses 400 mg IV or 500 mg orally every 12 hours; below 30 uses the daily regimen above.
IHD: 400 mg IV or 500 mg orally each evening. CVVHD: 400 mg IV every 8 hours or 500 mg orally every 12 hours. IV and oral choices are alternatives, not concurrent doses.
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
GlobalRPh v6.6 | RDM66-DIRECT-PHP-20260911 | Local library date 2026-09-11. Selected-card identity does not imply clinical verification.