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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.
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Clinical context remains essential
Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.
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Alimta - selected RX renal passage
Product / population
Pemetrexed (Alimta), IV lyophilized powder, adults
Renal method
Use the renal measure explicitly present in the RX passage.
Source revision
Mirror revision not established in the reviewed passage.
All record notes are retained here, including notes about sources not selected in this review.
Alimta - product and source limitations
The U.S. labeling directs withholding below CrCl 45. The dated Ontario monograph instructs discontinuation below that threshold. Verify the applicable treatment protocol before deciding whether treatment may resume.
What to reconcile: The U.S. labeling directs withholding below CrCl 45. The dated Ontario monograph instructs discontinuation below that threshold. Verify the applicable treatment protocol before deciding whether treatment may resume.
GlobalRPh RX List / product-label mirror · Pemetrexed (Alimta), IV lyophilized powder, adults
Renal method: Use the renal measure explicitly present in the RX passage. Source date: Mirror revision not established in the reviewed passage. Retrieved: 2026-11-07
Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Restriction or avoidance guidance. Read the specific threshold, age, formulation and dialysis exclusions; do not generalize across products.
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.