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CRESEMBA - adult prodrug dose and renal statement
Product / population
Adults; named product and route only. Selected dosing and renal summary, not the full prescribing information.
Renal method
No renal-function dose bands specified for this summary.
Source revision
DailyMed updated 2025-04-25.
Retrieved
2026-09-05
Local review status
Locally included source-specific summary. Regimen differences are not automatically resolved.
NIH/NLM DailyMed - U.S. product labeling · Adults; named product and route only. Selected dosing and renal summary, not the full prescribing information.
Renal method: No renal-function dose bands specified for this summary. Source date: DailyMed updated 2025-04-25. Retrieved: 2026-09-05
Locally included source-specific summary. Regimen differences are not automatically resolved.
Dosing / renal protocol and limits
For adult invasive aspergillosis or mucormycosis, give 372 mg isavuconazonium sulfate IV or orally every 8 hours for 6 doses, then 372 mg once daily. Begin maintenance 12-24 hours after the final loading dose. Each 372-mg prodrug dose equals 200 mg isavuconazole. Infuse IV doses over at least 1 hour, never as a bolus.
No adjustment is needed for mild, moderate or severe renal impairment, including ESRD. Isavuconazole is not readily removed by dialysis. Pediatric regimens and nasogastric preparation instructions require their separate label sections; this card is adult-only.
RDM30-075-isavuconazonium-1 · Source locator: CRESEMBA - adult prodrug dose and renal statement; renal/dosing sections and stated qualifiers
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
GlobalRPh v6.6 | RDM66-DIRECT-PHP-20260911 | Local library date 2026-09-11. Selected-card identity does not imply clinical verification.