GlobalRPh Renal Dosing Masterv6.6
Source review / handoff

Cephalexin

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

Selecting here opens the current stored cards. The pinned link below records their fingerprints. Do not enter patient information in links or searches.

Share or print this source review

1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

Copy is optional; the link can be selected and copied manually. No patient data or dose decision is collected.

Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

Check source scope before reading a dose

GlobalRPh RX List - KEFLEX

Product / population
Oral KEFLEX; renal table applies to adults and pediatric patients at least 15 years old.
Renal method
CrCl mL/min; no specified estimator in selected table.
Source revision
Source revision date not established in selected retrieval.
Retrieved
2026-09-07
Local review status
Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Documented differences and cautions on this drug

All record notes are retained here, including notes about sources not selected in this review.

Label maximum differs from institution-specific bacteremia dosing

The KEFLEX renal table caps the daily dose in moderate impairment. UCSF uses a different high-dose strategy for selected gram-negative bloodstream infection; Stanford also has a distinct HD regimen.

What to reconcile: The indication and regimen must stay together. Do not average the doses or relabel the bloodstream-infection schedule as a general renal dose.

Source difference identified; final patient-specific adjudication required.

Open this note and its source references

Label daily cap versus indication-specific institutional bloodstream doses

KEFLEX limits total daily dose to 1 g at CrCl 30-59 and has insufficient HD adjustment information. UCSF uses higher selected Gram-negative bloodstream-infection doses and supplies an intermittent-HD row.

What to reconcile: Assess infection eligibility, organism susceptibility, patient setting and institutional policy. Keep the complete institutional regimen separate from the label; do not transfer the bloodstream schedule to routine cystitis or children.

Source-specific interpretation; independent clinician adjudication pending.

Open this note and its source references
Rxlist

GlobalRPh RX List - KEFLEX

Open original reference

GlobalRPh-hosted RX List · Oral KEFLEX; renal table applies to adults and pediatric patients at least 15 years old.

Renal method: CrCl mL/min; no specified estimator in selected table.
Source date: Source revision date not established in selected retrieval.
Retrieved: 2026-09-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

CrCl >=60: no adjustment. CrCl 30-59: maximum total daily dose 1 g. CrCl 15-29: 250 mg every 8 or 12 hours. CrCl 5-14, not on dialysis: 250 mg every 24 hours. CrCl 1-4, not on dialysis: 250 mg every 48 or 60 hours. The source has insufficient information to recommend hemodialysis adjustment. Do not apply this adult/adolescent table to younger children or replace its unusual 60-hour option with an invented interval.

RDM42-rxlist-cephalexin-715dcb31c1-C1 · Source locator: Renal dosing Table 1 and footnote

Source identity and provenance
Source family
product_label_mirror
Source
https://globalrph.com/rx-list/keflex-drug/
Retrieved
2026-09-07
Renal-function method
CrCl mL/min; no specified estimator in selected table.
Source date/version
Source revision date not established in selected retrieval.
Hash meaning
SHA-256 of local authored summary only; not original HTML, PDF or SPL bytes.
Local summary SHA-256
d7699a9ca792120d70c0586a0d1c55ca853ff030c2513298d79df8126408fc16

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh v6.6 | RDM66-DIRECT-PHP-20260911 | Local library date 2026-09-11. Selected-card identity does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=cephalexin&s1=RDM42-rxlist-cephalexin-715dcb31c1&h1=465d4d082aaea13bb5a261ff9a0db90fd9bde2f36c93a5fc9182b5bb9865919e