GlobalRPh Renal Dosing Masterv6.6
Source review / handoff

Tenofovir disoproxil fumarate (Viread)

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

Tenofovir disoproxil fumarate 300 mg only, not tenofovir alafenamide or a fixed-dose combination.

The NIH addition is specifically tenofovir disoproxil fumarate (TDF). Do not apply it to tenofovir alafenamide (TAF) or a fixed-dose combination.

Check source scope before reading a dose

NIH adult ARV table - tenofovir disoproxil fumarate

Product / population
Adults; source-specific institutional guidance. Match route, indication and renal replacement modality.
Renal method
CrCl mL/min; single-agent TDF only
Source revision
Revision date not stated in the reviewed page.
Retrieved
2026-09-05
Local review status
Locally included source-specific summary. Regimen differences are not automatically resolved.
Professional

NIH adult ARV table - tenofovir disoproxil fumarate

Open original reference

NIH ClinicalInfo adult ARV panel · Adults; source-specific institutional guidance. Match route, indication and renal replacement modality.

Renal method: CrCl mL/min; single-agent TDF only
Source date: Revision date not stated in the reviewed page.
Retrieved: 2026-09-05

Locally included source-specific summary. Regimen differences are not automatically resolved.

Dosing / renal protocol and limits

Single-agent TDF: usual 300 mg orally daily. CrCl 30-49: 300 mg every 48 hours; 10-29: 300 mg every 72-96 hours; <10 without HD: no recommendation. HD: 300 mg every 7 days after dialysis. Do not apply this to TAF or fixed combinations.

RDM30-099-tenofovir-1 · Source locator: NIH adult ARV table - tenofovir disoproxil fumarate; renal/dosing sections and stated qualifiers

Source identity and provenance
Source
https://clinicalinfo.hiv.gov/en/guidelines/hiv-clinical-guidelines-adult-and-adolescent-arv/drug-characteristics-tables-renal-hepatic-insufficiency-full
Retrieved
2026-09-05
Renal-function method
CrCl mL/min; single-agent TDF only
Source date/version
Revision date not stated in the reviewed page.
Hash meaning
Locally authored summary text; not original SPL, HTML or PDF bytes
Local summary SHA-256
cdbdb281aa4fa64962797b211eaf68b5717d270c820600094140fe8e2036fdf5

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh v6.6 | RDM66-DIRECT-PHP-20260911 | Local library date 2026-09-11. Selected-card identity does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=tenofovir&s1=RDM30-099-tenofovir&h1=2c16175420e05d371214382725952faed7f1ce4c2e7233b8ee22d28afad9215e