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Aggrastat - labeled renal guidance
Product / population
Tirofiban (Aggrastat), adult IV treatment of non-ST-elevation acute coronary syndrome
Renal method
Cockcroft-Gault CrCl using actual body weight, mL/min
Source revision
DailyMed SPL version 3, effective 2025-01-01; posted Dec 26, 2024
DailyMed / product prescribing information · Tirofiban (Aggrastat), adult IV treatment of non-ST-elevation acute coronary syndrome
Renal method: Cockcroft-Gault CrCl using actual body weight, mL/min Source date: DailyMed SPL version 3, effective 2025-01-01; posted Dec 26, 2024 Retrieved: 2026-11-07
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
At CrCl <=60 mL/min, give 25 mcg/kg IV within 5 minutes, then 0.075 mcg/kg/min for up to 18 hours. Calculate Cockcroft-Gault with actual body weight. The renal reduction affects the infusion; confirm concentration and monitor bleeding and platelets.
RDM73-aggrastat-official-1 · Source locator: Renal guidance: 2.3 and 8.6
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.
