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Clinical context remains essential
Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.
The source HD summary does not distinguish indications. It must not override the indication-specific one-dose labialis or suppressive schedules without current-label review.
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GlobalRPh RX List - Valtrex
Product / population
Selected adult immunocompetent herpes-zoster regimen; not a genital-herpes, neonatal or pediatric renal schedule.
Renal method
Creatinine clearance in mL/min; adult indication-specific table.
Source revision
Source revision date not established in selected retrieval.
Retrieved
2026-09-07
Local review status
Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.
GlobalRPh-hosted RX List · Selected adult immunocompetent herpes-zoster regimen; not a genital-herpes, neonatal or pediatric renal schedule.
Renal method: Creatinine clearance in mL/min; adult indication-specific table. Source date: Source revision date not established in selected retrieval. Retrieved: 2026-09-07
Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.
Renal dosing, restrictions and evidence limits
For adult herpes zoster, the source lists 1 g every eight hours at CrCl >=50, 1 g every twelve hours at 30-49, 1 g every 24 hours at 10-29, and 500 mg every 24 hours below 10. The usual zoster course is seven days. On hemodialysis days, give the recommended dose after dialysis. The source has different rows for cold sores, genital-herpes treatment and suppression; do not transfer this zoster schedule to those indications. Pediatric use with CrCl below 50 mL/min/1.73 m2 lacks data. Renal accumulation and neurotoxicity precautions remain relevant even when an adjusted regimen is chosen.
RDM40-rxlist-valacyclovir-066f68064c-C1 · Source locator: Selected renal dosing, renal impairment, toxicity and pharmacokinetic subsections as identified in the summary.
Source-specific limits
Adult indication and pediatric evidence boundary are distinct; this is not the entire multi-indication table.
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
GlobalRPh v6.6 | RDM66-DIRECT-PHP-20260911 | Local library date 2026-09-11. Selected-card identity does not imply clinical verification.