GlobalRPh Renal Dosing Masterv6.6
Source review / handoff

Fosfomycin - oral

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

This qualitative statement remains a full source-specific protocol page. It is oral fosfomycin, not an IV protocol.

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UCSF - oral fosfomycin: cystitis regimens

Product / population
Adults; oral fosfomycin for cystitis only.
Renal method
CrCl in mL/min where specified; no equation inferred.
Source revision
Revision date not stated in the reviewed page.
Retrieved
2026-09-05
Local review status
Locally included source-specific summary. Regimen differences are not automatically resolved.

Documented differences and cautions on this drug

All record notes are retained here, including notes about sources not selected in this review.

Labeled single-dose cystitis versus repeated institutional dosing

MONUROL labeling is limited to uncomplicated cystitis. UCSF separately supplies repeated oral doses for complicated cystitis and leaves CrCl exactly 50 unassigned between >50 and <50.

What to reconcile: Document the institutional/off-label rationale and exact renal band. Do not use these oral schedules for pyelonephritis or IV CONTEPO.

Source-specific interpretation; independent clinician adjudication pending.

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Professional

UCSF - oral fosfomycin: cystitis regimens

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UCSF Infectious Diseases Management Program · Adults; oral fosfomycin for cystitis only.

Renal method: CrCl in mL/min where specified; no equation inferred.
Source date: Revision date not stated in the reviewed page.
Retrieved: 2026-09-05

Locally included source-specific summary. Regimen differences are not automatically resolved.

Dosing / renal protocol and limits

Uncomplicated cystitis: 3 g orally once, including renal impairment. Complicated cystitis is an institutional, off-label regimen: CrCl >50 mL/min, 3 g every 2 days for three doses; CrCl <50, 3 g every 3 days for three doses. Exactly 50 is not assigned by the webpage.

During intermittent HD, give the uncomplicated single dose after HD; for complicated cystitis, give 3 g every 3 days for three doses after HD. Continuous-HD data are not provided. These instructions concern oral fosfomycin, not intravenous products.

RDM30-029-fosfomycin-1 · Source locator: UCSF - oral fosfomycin: cystitis regimens; renal/dosing sections and stated qualifiers

Source identity and provenance
Source
https://idmp.ucsf.edu/content/fosfomycin-po
Retrieved
2026-09-05
Renal-function method
CrCl in mL/min where specified; no equation inferred.
Source date/version
Revision date not stated in the reviewed page.
Hash meaning
Locally authored summary text; not original SPL, HTML or PDF bytes
Local summary SHA-256
c2146cb1fea46178f7d199dc215b434d8a04f873af9c0f5bbc0a6975eb7e51fb

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh v6.6 | RDM66-DIRECT-PHP-20260911 | Local library date 2026-09-11. Selected-card identity does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=fosfomycin&s1=RDM30-029-fosfomycin&h1=0c4d4db852c84d4856ad0de9540be26f7ed5b2baa3ce0de4c43f906d5da977d8