GlobalRPh Renal Dosing Masterv6.6
Source review / handoff

Tigecycline (Tygacil)

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

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UCSF - tigecycline

Product / population
Adults; source-specific institutional guidance. Match route, indication and renal replacement modality.
Renal method
Renal reduction not recommended; hepatic adjustment is separate.
Source revision
Revision date not stated in the reviewed page.
Retrieved
2026-09-05
Local review status
Locally included source-specific summary. Regimen differences are not automatically resolved.
Professional

UCSF - tigecycline

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UCSF Infectious Diseases Management Program · Adults; source-specific institutional guidance. Match route, indication and renal replacement modality.

Renal method: Renal reduction not recommended; hepatic adjustment is separate.
Source date: Revision date not stated in the reviewed page.
Retrieved: 2026-09-05

Locally included source-specific summary. Regimen differences are not automatically resolved.

Dosing / renal protocol and limits

Adult IV treatment starts with 100 mg once, followed by 50 mg every 12 hours. Renal dysfunction and hemodialysis do not change that schedule. Severe hepatic dysfunction instead uses the same loading dose followed by 25 mg every 12 hours.

Some selected infections may receive 200 mg initially followed by 100 mg every 12 hours, but only with infectious-diseases/stewardship input. The higher schedule is not a renal adjustment and must not replace the standard schedule automatically.

RDM30-036-tigecycline-1 · Source locator: UCSF - tigecycline; renal/dosing sections and stated qualifiers

Source identity and provenance
Source
https://idmp.ucsf.edu/content/tigecycline
Retrieved
2026-09-05
Renal-function method
Renal reduction not recommended; hepatic adjustment is separate.
Source date/version
Revision date not stated in the reviewed page.
Hash meaning
Locally authored summary text; not original SPL, HTML or PDF bytes
Local summary SHA-256
b8d69af4c539a752323412103a713c870e21194d39534c1262466b20f04e3018

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh v6.6 | RDM66-DIRECT-PHP-20260911 | Local library date 2026-09-11. Selected-card identity does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=tigecycline&s1=RDM30-036-tigecycline&h1=085765c9655db789aae9d28331d23ccf49ba4ad873bf1091e14f789dd66d9a96