One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.
1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.
Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.
Renal function alone is insufficient: use the route-specific matrix with lean body weight, clinical response, interactions, electrolytes and measured concentrations. Digoxin immune Fab is an antidote, not another digoxin formulation.
What to reconcile: Use the IV matrix and full injection precautions; keep dose units in mcg and separate this from immune Fab.
Open this note and its source referencesConfirm corrected renal measure, lean weight, route and specimen timing. The complete matrix is a source table, not a patient-specific dose recommendation.
Adult reference: CrCl in this table is corrected to 70 kg or 1.73 m2, not an interchangeable unindexed clearance. These are maintenance doses, not loading doses.
Give IV doses over at least 5 minutes. Oral and IV doses are not interchangeable 1:1. Sample before the next dose or at least 6 hours later; interpret with symptoms, electrolytes and interactions.
Display filter only. No dose is selected or calculated. Copy and print retain the complete matrix.
| Corrected CrCl (mL/min) | 40 kg lean weight (mcg once daily) | 50 kg lean weight (mcg once daily) | 60 kg lean weight (mcg once daily) | 70 kg lean weight (mcg once daily) | 80 kg lean weight (mcg once daily) | 90 kg lean weight (mcg once daily) | 100 kg lean weight (mcg once daily) | Days to steady state without loading |
|---|---|---|---|---|---|---|---|---|
| 10 | 64 | 80 | 96 | 112 | 128 | 144 | 160 | 19 |
| 20 | 72 | 90 | 108 | 126 | 144 | 162 | 180 | 16 |
| 30 | 80 | 100 | 120 | 140 | 160 | 180 | 200 | 14 |
| 40 | 88 | 110 | 132 | 154 | 176 | 198 | 220 | 13 |
| 50 | 96 | 120 | 144 | 168 | 192 | 216 | 240 | 12 |
| 60 | 104 | 130 | 156 | 182 | 208 | 234 | 260 | 11 |
| 70 | 112 | 140 | 168 | 196 | 224 | 252 | 280 | 10 |
| 80 | 120 | 150 | 180 | 210 | 240 | 270 | 300 | 9 |
| 90 | 128 | 160 | 192 | 224 | 256 | 288 | 320 | 8 |
| 100 | 136 | 170 | 204 | 238 | 272 | 306 | 340 | 7 |
Label values assume average body composition; use both corrected CrCl and lean weight. No interpolation, automatic selection or rounding is performed.
Digoxin IV maintenance matrix - mcg ONCE daily
| Corrected CrCl (mL/min) | 40 kg lean weight (mcg once daily) | 50 kg lean weight (mcg once daily) | 60 kg lean weight (mcg once daily) | 70 kg lean weight (mcg once daily) | 80 kg lean weight (mcg once daily) | 90 kg lean weight (mcg once daily) | 100 kg lean weight (mcg once daily) | Days to steady state without loading |
|---|---|---|---|---|---|---|---|---|
| 10 | 64 | 80 | 96 | 112 | 128 | 144 | 160 | 19 |
| 20 | 72 | 90 | 108 | 126 | 144 | 162 | 180 | 16 |
| 30 | 80 | 100 | 120 | 140 | 160 | 180 | 200 | 14 |
| 40 | 88 | 110 | 132 | 154 | 176 | 198 | 220 | 13 |
| 50 | 96 | 120 | 144 | 168 | 192 | 216 | 240 | 12 |
| 60 | 104 | 130 | 156 | 182 | 208 | 234 | 260 | 11 |
| 70 | 112 | 140 | 168 | 196 | 224 | 252 | 280 | 10 |
| 80 | 120 | 150 | 180 | 210 | 240 | 270 | 300 | 9 |
| 90 | 128 | 160 | 192 | 224 | 256 | 288 | 320 | 8 |
| 100 | 136 | 170 | 204 | 238 | 272 | 306 | 340 | 7 |
Label values assume average body composition; use both corrected CrCl and lean weight. No interpolation, automatic selection or rounding is performed.
Adult reference: CrCl in this table is corrected to 70 kg or 1.73 m2, not an interchangeable unindexed clearance. These are maintenance doses, not loading doses.
Give IV doses over at least 5 minutes. Oral and IV doses are not interchangeable 1:1. Sample before the next dose or at least 6 hours later; interpret with symptoms, electrolytes and interactions.
RDM64-official-digoxin-injection-797c6716ea-C1 · Source locator: Sections 2.1, 2.3 Table 3 including footnotes, 2.5-2.6 and 8.6.
Adult reference: CrCl in this table is corrected to 70 kg or 1.73 m2, not an interchangeable unindexed clearance. These are maintenance doses, not loading doses.
Give IV doses over at least 5 minutes. Oral and IV doses are not interchangeable 1:1. Sample before the next dose or at least 6 hours later; interpret with symptoms, electrolytes and interactions.
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=digoxin-injection&s1=RDM64-official-digoxin-injection-797c6716ea&h1=042670dff3d046522320305da5bd742aea767860d2f10b324e40f5bcbd534240