Renal function alone is insufficient: use the route-specific matrix with lean body weight, clinical response, interactions, electrolytes and measured concentrations. Digoxin immune Fab is an antidote, not another digoxin formulation.
Before applying: Use the IV matrix and full injection precautions; keep dose units in mcg and separate this from immune Fab.
Confirm the product, indication and renal measure. The selected summary is not a complete prescribing monograph.
Choose a source to read (2)
Display order is not a clinical ranking. Date of retrieval is not the label revision date. Sources are never merged into one regimen. Other sources and conflicts remain below.
Official source
Digoxin - intravenous injection
Product / population
Adult IV maintenance excerpt from label Table 3; no pediatric dosing or loading algorithm.
Renal measure
Label-corrected creatinine clearance to 70 kg or 1.73 m2, plus lean body weight.
Before using this finding
Confirm corrected renal measure, lean weight, route and specimen timing. The complete matrix is a source table, not a patient-specific dose recommendation.
Renal guidance and important limits
Limits that apply to these rows
Adult reference: CrCl in this table is corrected to 70 kg or 1.73 m2, not an interchangeable unindexed clearance. These are maintenance doses, not loading doses.
Give IV doses over at least 5 minutes. Oral and IV doses are not interchangeable 1:1. Sample before the next dose or at least 6 hours later; interpret with symptoms, electrolytes and interactions.
Open complete source table: Digoxin IV maintenance matrix - mcg ONCE daily
Display filter only. No dose is selected or calculated. Copy and print retain the complete matrix.
Digoxin IV maintenance matrix - mcg ONCE daily
Corrected CrCl (mL/min)
40 kg lean weight (mcg once daily)
50 kg lean weight (mcg once daily)
60 kg lean weight (mcg once daily)
70 kg lean weight (mcg once daily)
80 kg lean weight (mcg once daily)
90 kg lean weight (mcg once daily)
100 kg lean weight (mcg once daily)
Days to steady state without loading
10
64
80
96
112
128
144
160
19
20
72
90
108
126
144
162
180
16
30
80
100
120
140
160
180
200
14
40
88
110
132
154
176
198
220
13
50
96
120
144
168
192
216
240
12
60
104
130
156
182
208
234
260
11
70
112
140
168
196
224
252
280
10
80
120
150
180
210
240
270
300
9
90
128
160
192
224
256
288
320
8
100
136
170
204
238
272
306
340
7
Label values assume average body composition; use both corrected CrCl and lean weight. No interpolation, automatic selection or rounding is performed.
Read the retained text before reformatting
Digoxin IV maintenance matrix - mcg ONCE daily
Corrected CrCl (mL/min)
40 kg lean weight (mcg once daily)
50 kg lean weight (mcg once daily)
60 kg lean weight (mcg once daily)
70 kg lean weight (mcg once daily)
80 kg lean weight (mcg once daily)
90 kg lean weight (mcg once daily)
100 kg lean weight (mcg once daily)
Days to steady state without loading
10
64
80
96
112
128
144
160
19
20
72
90
108
126
144
162
180
16
30
80
100
120
140
160
180
200
14
40
88
110
132
154
176
198
220
13
50
96
120
144
168
192
216
240
12
60
104
130
156
182
208
234
260
11
70
112
140
168
196
224
252
280
10
80
120
150
180
210
240
270
300
9
90
128
160
192
224
256
288
320
8
100
136
170
204
238
272
306
340
7
Label values assume average body composition; use both corrected CrCl and lean weight. No interpolation, automatic selection or rounding is performed.
Adult reference: CrCl in this table is corrected to 70 kg or 1.73 m2, not an interchangeable unindexed clearance. These are maintenance doses, not loading doses.
Give IV doses over at least 5 minutes. Oral and IV doses are not interchangeable 1:1. Sample before the next dose or at least 6 hours later; interpret with symptoms, electrolytes and interactions.
Source revision: 6/2025 | Retrieved: 2026-09-10. Retrieval date is not the revision date.
All sources, comparison tools and evidence navigation
Source-first renal review
Evidence sources and renal implications
Choose a source to jump directly to its locally stored result. Qualitative precautions and evidence gaps remain visible even when no numerical clearance schedule is supplied.
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
Before using this finding
Confirm corrected renal measure, lean weight, route and specimen timing. The complete matrix is a source table, not a patient-specific dose recommendation.
Adult IV maintenance excerpt from label Table 3; no pediatric dosing or loading algorithm.
Renal method: Label-corrected creatinine clearance to 70 kg or 1.73 m2, plus lean body weight. Retrieved: 2026-09-10
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Renal-context checklist: population, kidney trend and dialysis
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These are specific issues found during source review, not an automated judgment that one source is universally correct. A label mirror and its original label are not independent evidence.
source scope and renal guidance
Before use: Digoxin - intravenous injection
Renal function alone is insufficient: use the route-specific matrix with lean body weight, clinical response, interactions, electrolytes and measured concentrations. Digoxin immune Fab is an antidote, not another digoxin formulation.
How to use this: Use the IV matrix and full injection precautions; keep dose units in mcg and separate this from immune Fab.
Choose a source, then jump to its renal or dialysis section. These links locate stored text; they do not merge regimens or certify that sources agree.
New source summary - independent clinical review pending. Summaries of the identified label sections are included locally. Source import and numeric transcription checks are not independent two-reference validation. Do not treat this card as an approved institutional dosing protocol.
Official source
Digoxin - intravenous injection
Adult IV maintenance excerpt from label Table 3; no pediatric dosing or loading algorithm.
Method: Label-corrected creatinine clearance to 70 kg or 1.73 m2, plus lean body weight.
No dialysis or renal heading shown? Read the complete source summary. Absence of a heading is not evidence that dose adjustment is unnecessary.
Compare or copy source versions
All content below is stored locally. Read a whole source version; do not combine its dose with another source's interval, renal metric or dialysis assumptions.
Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
DailyMed / NLM exact product labeling · Adult IV maintenance excerpt from label Table 3; no pediatric dosing or loading algorithm.
Renal method: Label-corrected creatinine clearance to 70 kg or 1.73 m2, plus lean body weight. Source date: 6/2025 Retrieved: 2026-09-10
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
Before using this finding
Confirm corrected renal measure, lean weight, route and specimen timing. The complete matrix is a source table, not a patient-specific dose recommendation.
Selected source sections stored locally. Not a complete monograph or independent clinical approval.
Renal guidance and important limits
Limits that apply to these rows
Adult reference: CrCl in this table is corrected to 70 kg or 1.73 m2, not an interchangeable unindexed clearance. These are maintenance doses, not loading doses.
Give IV doses over at least 5 minutes. Oral and IV doses are not interchangeable 1:1. Sample before the next dose or at least 6 hours later; interpret with symptoms, electrolytes and interactions.
Open complete source table: Digoxin IV maintenance matrix - mcg ONCE daily
Display filter only. No dose is selected or calculated. Copy and print retain the complete matrix.
Digoxin IV maintenance matrix - mcg ONCE daily
Corrected CrCl (mL/min)
40 kg lean weight (mcg once daily)
50 kg lean weight (mcg once daily)
60 kg lean weight (mcg once daily)
70 kg lean weight (mcg once daily)
80 kg lean weight (mcg once daily)
90 kg lean weight (mcg once daily)
100 kg lean weight (mcg once daily)
Days to steady state without loading
10
64
80
96
112
128
144
160
19
20
72
90
108
126
144
162
180
16
30
80
100
120
140
160
180
200
14
40
88
110
132
154
176
198
220
13
50
96
120
144
168
192
216
240
12
60
104
130
156
182
208
234
260
11
70
112
140
168
196
224
252
280
10
80
120
150
180
210
240
270
300
9
90
128
160
192
224
256
288
320
8
100
136
170
204
238
272
306
340
7
Label values assume average body composition; use both corrected CrCl and lean weight. No interpolation, automatic selection or rounding is performed.
Read the retained text before reformatting
Digoxin IV maintenance matrix - mcg ONCE daily
Corrected CrCl (mL/min)
40 kg lean weight (mcg once daily)
50 kg lean weight (mcg once daily)
60 kg lean weight (mcg once daily)
70 kg lean weight (mcg once daily)
80 kg lean weight (mcg once daily)
90 kg lean weight (mcg once daily)
100 kg lean weight (mcg once daily)
Days to steady state without loading
10
64
80
96
112
128
144
160
19
20
72
90
108
126
144
162
180
16
30
80
100
120
140
160
180
200
14
40
88
110
132
154
176
198
220
13
50
96
120
144
168
192
216
240
12
60
104
130
156
182
208
234
260
11
70
112
140
168
196
224
252
280
10
80
120
150
180
210
240
270
300
9
90
128
160
192
224
256
288
320
8
100
136
170
204
238
272
306
340
7
Label values assume average body composition; use both corrected CrCl and lean weight. No interpolation, automatic selection or rounding is performed.
Adult reference: CrCl in this table is corrected to 70 kg or 1.73 m2, not an interchangeable unindexed clearance. These are maintenance doses, not loading doses.
Give IV doses over at least 5 minutes. Oral and IV doses are not interchangeable 1:1. Sample before the next dose or at least 6 hours later; interpret with symptoms, electrolytes and interactions.
RDM64-official-digoxin-injection-797c6716ea-C1 · Source locator: Sections 2.1, 2.3 Table 3 including footnotes, 2.5-2.6 and 8.6.
Source-specific limits
Adult reference: CrCl in this table is corrected to 70 kg or 1.73 m2, not an interchangeable unindexed clearance. These are maintenance doses, not loading doses.
Give IV doses over at least 5 minutes. Oral and IV doses are not interchangeable 1:1. Sample before the next dose or at least 6 hours later; interpret with symptoms, electrolytes and interactions.
GlobalRPh-hosted RX List · Adult IV digoxin; pediatric and IM material on the source page is outside this summary.
Renal method: Label-corrected creatinine clearance and lean body weight. Source date: Revision not established in selected retrieval Retrieved: 2026-09-10
Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
Before using this finding
Use the IV matrix and full injection precautions; keep dose units in mcg and separate this from immune Fab.
Selected source sections stored locally. Not a complete monograph or independent clinical approval.
Renal guidance and important limits
Limits that apply to these rows
The mirror and newly checked injection label require lean body weight and renal function for maintenance dosing.
Do not apply the oral matrix to IV doses or interpret dialysis as a reason for a guessed replacement dose.
Injection maintenance scope
Decision
Source-specific instruction
Renal impairment
Smaller maintenance requirements and a longer interval to steady state; use the IV matrix.
Administration
Administer over at least 5 minutes; not a rapid bolus.
Read the retained text before reformatting
Injection maintenance scope
Decision
Source-specific instruction
Renal impairment
Smaller maintenance requirements and a longer interval to steady state; use the IV matrix.
Administration
Administer over at least 5 minutes; not a rapid bolus.
The mirror and newly checked injection label require lean body weight and renal function for maintenance dosing.
Do not apply the oral matrix to IV doses or interpret dialysis as a reason for a guessed replacement dose.
RDM64-rxlist-digoxin-injection-025609b9f0-C1 · Source locator: Dosage: important administration, maintenance and monitoring; Renal Impairment.
Source-specific limits
The mirror and newly checked injection label require lean body weight and renal function for maintenance dosing.
Do not apply the oral matrix to IV doses or interpret dialysis as a reason for a guessed replacement dose.
Additional summaries stored on this page: 1 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.
This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.