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TYGACIL - adult renal and hepatic distinctions
Product / population
Adults; named product and route only. Selected dosing and renal summary, not the full prescribing information.
Renal method
No renal-function dose bands specified for this summary.
Source revision
DailyMed updated 2025-11-18.
Retrieved
2026-09-05
Local review status
Locally included source-specific summary. Regimen differences are not automatically resolved.
NIH/NLM DailyMed - U.S. product labeling · Adults; named product and route only. Selected dosing and renal summary, not the full prescribing information.
Renal method: No renal-function dose bands specified for this summary. Source date: DailyMed updated 2025-11-18. Retrieved: 2026-09-05
Locally included source-specific summary. Regimen differences are not automatically resolved.
Dosing / renal protocol and limits
Adult labeled infections: 100 mg IV loading dose, then 50 mg IV every 12 hours; infuse over approximately 30-60 minutes. Renal impairment and hemodialysis do not require dose changes; hemodialysis does not remove tigecycline.
Severe hepatic impairment is different: retain the 100-mg loading dose but use 25 mg every 12 hours for Child-Pugh C. The boxed warning identifies increased all-cause mortality; reserve use when suitable alternatives are lacking. Hospital-acquired/ventilator-associated pneumonia and diabetic-foot infection are not labeled indications. Do not infer pediatric dosing from this adult regimen.
RDM30-078-tigecycline-1 · Source locator: TYGACIL - adult renal and hepatic distinctions; renal/dosing sections and stated qualifiers
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
GlobalRPh v6.6 | RDM66-DIRECT-PHP-20260911 | Local library date 2026-09-11. Selected-card identity does not imply clinical verification.