GlobalRPh Renal Dosing Masterv6.6
Source-specific lookup | Version 6.6

Find the guidance.
Keep the qualifications.

Look for a clinical topic across locally stored sources. Every result opens the complete stored source and its drug-level cautions.

A pharmacokinetic observation is not a dosing instruction

The finding-type filter groups stored source categories, not evidence quality. Dose instructions, no-adjustment statements, qualitative cautions and PK-only observations stay separate. A source may discuss other issues beyond its primary category. Old cards are not reclassified; choose all types or the unclassified group when a narrow search misses useful text. Counts describe the full library, not just the current search.

Match the source's renal measure, not just the number

406 source summaries have a manually checked measure label; 1013 remain unclassified. Classification covers selected v4.2 through v5.9 summaries. Older and unresolved-method text remains available. Use the optional unclassified-source setting when narrowing by renal measure; other filters still apply. A narrow filter can omit relevant dosing guidance.

Measured urine-collection CrCl, estimated CrCl, BSA-indexed CrCl and indexed eGFR are not interchangeable simply because numbers look similar. A percentage-of-normal statement is not a numeric eGFR cutoff. This filter makes no calculation, conversion or recommendation.

Read renal-measure guidance

Source family and topic are not prescribing decisions

Qualified no-adjustment statements apply only to the source's stated scope. A pharmacokinetic observation is not automatically a dosing recommendation. "Not studied" is not "no adjustment." Read restrictions, interactions, monitoring and dialysis context even when searching only for a dose.

A label mirror and its original label are not independent corroboration. Source families identify storage provenance, not quality, currency or clinical approval. Professional material can include institutional policy, research or regulatory notices; read the actual source. Recent source summaries have manually assigned topic labels. Earlier summaries use their existing content categories; many remain unclassified. The optional topic-unclassified setting is off by default. It includes only unclassified candidates, not sources labeled solely for a different topic. Renal measure, family and text filters still apply. Labels describe selected stored content, not evidence quality, source agreement or independent clinical approval. A narrow filter can miss relevant material.

168 matching source entries. Showing 1-16; page 1 / 11.

Not classified by finding typeProfessional / research / regulatoryUnclassified / original material

Abacavir

NIH adult ARV table - single-agent abacavir

Professional / research / regulatory | Existing source category; topic coverage may be incomplete

Product / population: Adults; source-specific institutional guidance. Match route, indication and renal replacement modality.

Renal measure: Most ARV label thresholds use Cockcroft-Gault CrCl

Measure label: Measure not yet classified. Read the exact source wording above.

Locally included source-specific summary. Regimen differences are not automatically resolved.

Source dates and additional notes

Source revision: Revision date not stated in the reviewed page.
Retrieved: 2026-09-05

No difference note is recorded here. This does not certify agreement.

Dose / interval guidanceProfessional / research / regulatoryRestrictions / avoidanceUnstudied ranges / evidence gaps

Abacavir/lamivudine (KIVEXA, international source)

NIH adult abacavir/lamivudine - U.S.-focused comparator

Professional / research / regulatory | Manually labeled selected summary

Product / population: Adult U.S.-focused ABC/3TC fixed-combination guidance used to compare an international KIVEXA source; not proof of KIVEXA U.S. approval.

Renal measure: CrCl mL/min; most ARV label recommendations use Cockcroft-Gault.

Measure label: CrCl in mL/min. Read the exact source wording above.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Source dates and additional notes

Source revision: Source revision date not established in selected retrieval.
Retrieved: 2026-09-07

1 documented source differences / product cautions

Not classified by finding typeProfessional / research / regulatoryUnclassified / original material

Acyclovir

UCSF - acyclovir intravenous: HSV, VZV and dialysis

Professional / research / regulatory | Existing source category; topic coverage may be incomplete

Product / population: Adults; IV acyclovir only. Separate from oral and topical formulations.

Renal measure: CrCl in mL/min where specified; no equation inferred.

Measure label: Measure not yet classified. Read the exact source wording above.

Locally included source-specific summary. Regimen differences are not automatically resolved.

Source dates and additional notes

Source revision: Revision date not stated in the reviewed page.
Retrieved: 2026-09-05

Drug-level caution

The original page contains two different IV renal band sets (25/50 versus 30/50) and an indexed CrCl table. They are preserved separately, not reconciled into one recommendation. Confirm the applicable current product label before clinical use.

No difference note is recorded here. This does not certify agreement.

Not classified by finding typeProfessional / research / regulatoryUnclassified / original material

Acyclovir

UCSF - oral acyclovir: HSV and VZV

Professional / research / regulatory | Existing source category; topic coverage may be incomplete

Product / population: Adults; oral acyclovir only.

Renal measure: CrCl in mL/min where specified; no equation inferred.

Measure label: Measure not yet classified. Read the exact source wording above.

Locally included source-specific summary. Regimen differences are not automatically resolved.

Source dates and additional notes

Source revision: Revision date not stated in the reviewed page.
Retrieved: 2026-09-05

Drug-level caution

The original page contains two different IV renal band sets (25/50 versus 30/50) and an indexed CrCl table. They are preserved separately, not reconciled into one recommendation. Confirm the applicable current product label before clinical use.

No difference note is recorded here. This does not certify agreement.

Dose / interval guidanceProfessional / research / regulatoryQualified no-adjustment statementsUnstudied ranges / evidence gaps

Ado-trastuzumab emtansine (KADCYLA)

eviQ metastatic breast trastuzumab emtansine - kidney guidance

Professional / research / regulatory | Manually labeled selected summary

Product / population: Australian metastatic breast cancer protocol; institutional/consensus-derived perspective, not a U.S. label replacement.

Renal measure: Indexed eGFR mL/min/1.73 m2; kidney replacement therapy considered separately.

Measure label: Indexed eGFR / GFR. Read the exact source wording above.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Source dates and additional notes

Source revision: Source revision date not established in selected retrieval.
Retrieved: 2026-09-07

1 documented source differences / product cautions

Professional guidance with defined scopeProfessional / research / regulatoryDose / interval guidanceMonitoring / toxicity / cautions

Allopurinol

2020 ACR gout guideline - initiation versus titrated maintenance

Professional / research / regulatory | Manually labeled selected summary

Product / population: 2020 ACR gout guideline; urate-lowering treatment selection and titration, not cancer-therapy or dialysis-specific dosing.

Renal measure: CKD stage and serial serum urate; not a numerical CrCl dosing table

Measure label: Measure not yet classified. Read the exact source wording above.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Source dates and additional notes

Source revision: 2020
Retrieved: 2026-09-09

Full primary guideline text retrieved; selected initiation and titration recommendations summarized.

This is the dated 2020 guideline, not a claim that every subsequent guideline or trial was reviewed.

2 documented source differences / product cautions

Not classified by finding typeProfessional / research / regulatoryUnclassified / original material

Amikacin

Stanford - extended-interval amikacin starting schedule

Professional / research / regulatory | Existing source category; topic coverage may be incomplete

Product / population: Adults; gram-negative extended-interval method

Renal measure: CrCl mL/min plus measured level

Measure label: Measure not yet classified. Read the exact source wording above.

Locally included source-specific summary. Regimen differences are not automatically resolved.

Source dates and additional notes

Source revision: Revision date not stated in the reviewed page.
Retrieved: 2026-09-05

Drug-level caution

The source opening dose and its subsequent 15 mg/kg/day discussion are not interchangeable. Both are retained as historical text; no automatic aminoglycoside dose calculation is generated from them.

No difference note is recorded here. This does not certify agreement.

Not classified by finding typeProfessional / research / regulatoryUnclassified / original material

Amoxicillin

UCSF - amoxicillin

Professional / research / regulatory | Existing source category; topic coverage may be incomplete

Product / population: Adults; oral amoxicillin only, not amoxicillin/clavulanate.

Renal measure: CrCl in mL/min where specified; no equation inferred.

Measure label: Measure not yet classified. Read the exact source wording above.

Locally included source-specific summary. Regimen differences are not automatically resolved.

Source dates and additional notes

Source revision: Revision date not stated in the reviewed page.
Retrieved: 2026-09-05

2 documented source differences / product cautions

Dose / interval guidanceProfessional / research / regulatoryMonitoring / toxicity / cautions

Amoxicillin

Galway GAPP - amoxicillin IV/PO

Professional / research / regulatory | Manually labeled selected summary

Product / population: Hospitalized adults; Irish institutional guidance, not a US product label.

Renal measure: Indexed eGFR, mL/min/1.73 m2; source identifies exceptions requiring Cockcroft-Gault.

Measure label: Measure not yet classified. Read the exact source wording above.

Selected source sections stored locally. Not a complete monograph or independent clinical approval.

Source dates and additional notes

Source revision: Revision not established in selected retrieval
Retrieved: 2026-09-10

The asterisk marks significant differences among references. Usual dosing means the local normal-renal/hepatic regimen.

CRRT is outside this guideline. Route, severity and renal measure must remain attached; do not combine its interval with another source dose.

2 documented source differences / product cautions

Dose / interval guidanceProfessional / research / regulatoryMonitoring / toxicity / cautions

Amoxicillin

UCSF - amoxicillin oral renal and dialysis tables

Professional / research / regulatory | Manually labeled selected summary

Product / population: Adults; oral dosing for selected indications.

Renal measure: CrCl, mL/min; dialysis assumptions stated separately.

Measure label: CrCl in mL/min. Read the exact source wording above.

Selected source sections stored locally. Not a complete monograph or independent clinical approval.

Source dates and additional notes

Source revision: Revision not established in selected retrieval
Retrieved: 2026-09-10

Exactly 30 mL/min is not assigned by the printed >30 / 10-29 headings; seek clarification rather than interpolate.

IHD assumes high-flux HD. Continuous guidance assumes CVVHD at 2 L/hour ultrafiltration with residual GFR <10; limited data/local expert opinion.

2 documented source differences / product cautions

Not classified by finding typeProfessional / research / regulatoryUnclassified / original material

Amoxicillin/Clav

UCSF - amoxicillin/clavulanate: standard and bloodstream-infection regimens

Professional / research / regulatory | Existing source category; topic coverage may be incomplete

Product / population: Adults; oral immediate-release amoxicillin/clavulanate. Separate indication-specific institutional schedules.

Renal measure: CrCl in mL/min where specified; no equation inferred.

Measure label: Measure not yet classified. Read the exact source wording above.

Locally included source-specific summary. Regimen differences are not automatically resolved.

Source dates and additional notes

Source revision: Revision date not stated in the reviewed page.
Retrieved: 2026-09-05

Drug-level caution

The source summary mentions an after-dialysis dose; the source package-insert paragraph says both during and at the end of dialysis. Both statements are retained and require product-specific reconciliation.

1 documented source differences / product cautions

Not classified by finding typeProfessional / research / regulatoryUnclassified / original material

Amphotericin B liposomal (AmBisome)

UCSF AmBisome - renal and dialysis protocols

Professional / research / regulatory | Existing source category; topic coverage may be incomplete

Product / population: Adults receiving intravenous liposomal amphotericin B, specifically AmBisome. Not interchangeable with deoxycholate, lipid-complex or other amphotericin formulations.

Renal measure: No renal dose reduction; source-specific weight convention

Measure label: Measure not yet classified. Read the exact source wording above.

Separate professional-source protocol; not automatically equivalent to product labeling.

Source dates and additional notes

Source revision: Revision date not stated on the reviewed page.
Retrieved: 2026-09-05

The cryptococcal 4 mg/kg combination regimen differs from the label's 6 mg/kg regimen; preserve the entire selected treatment plan. The source's optional saline hydration requires assessment of fluid tolerance; it is not an instruction to mix saline into AmBisome.

No difference note is recorded here. This does not certify agreement.

Not classified by finding typeProfessional / research / regulatoryUnclassified / original material

Ampicillin

Stanford adult Ampicillin

Professional / research / regulatory | Existing source category; topic coverage may be incomplete

Product / population: Adult institutional dosing; not a manufacturer-label replacement.

Renal measure: Not separately normalized; read the full source.

Measure label: Measure not yet classified. Read the exact source wording above.

Source-read local summary; source-specific recommendations are not automatically interchangeable.

Source dates and additional notes

Source revision: Antibiotic Subcommittee approved August 2026
Retrieved: 2026-09-05

No difference note is recorded here. This does not certify agreement.

Not classified by finding typeProfessional / research / regulatoryUnclassified / original material

Ampicillin/Sulbactam

UCSF - ampicillin/sulbactam

Professional / research / regulatory | Existing source category; topic coverage may be incomplete

Product / population: Adults; source-specific institutional guidance. Match route, indication and renal replacement modality.

Renal measure: CrCl in mL/min where specified; no equation inferred.

Measure label: Measure not yet classified. Read the exact source wording above.

Locally included source-specific summary. Regimen differences are not automatically resolved.

Source dates and additional notes

Source revision: Revision date not stated in the reviewed page.
Retrieved: 2026-09-05

Drug-level caution

The source summary and source table use slightly different boundary notation at CrCl 30. The original indexed table heading and accompanying Cockcroft-Gault formula are retained; renal-function normalization must be confirmed before prescribing.

2 documented source differences / product cautions

Dose / interval guidanceProfessional / research / regulatoryDose / interval guidance

Ampicillin/Sulbactam

UCSF: ampicillin/sulbactam adult institutional dosing

Professional / research / regulatory | Existing source category; topic coverage may be incomplete

Product / population: Adult institutional antimicrobial dosing; standard and separately ID-directed CRAB pathways.

Renal measure: CrCl in mL/min; intermittent versus continuous hemodialysis; source-specific boundaries

Measure label: Measure not yet classified. Read the exact source wording above.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Source dates and additional notes

Source revision: Source revision date not established in selected retrieval.
Retrieved: 2026-09-07

Drug-level caution

The source summary and source table use slightly different boundary notation at CrCl 30. The original indexed table heading and accompanying Cockcroft-Gault formula are retained; renal-function normalization must be confirmed before prescribing.

2 documented source differences / product cautions

Not classified by finding typeProfessional / research / regulatoryUnclassified / original material

Apixaban - adult oral tablets

AAFP - correction separating AF and VTE dose rules

Professional / research / regulatory | Existing source category; topic coverage may be incomplete

Product / population: Adults; source-specific institutional guidance. Match route, indication and renal replacement modality.

Renal measure: Indication-specific age/weight/serum-creatinine criteria; do not substitute a universal CrCl cutoff

Measure label: Measure not yet classified. Read the exact source wording above.

Locally included source-specific summary. Regimen differences are not automatically resolved.

Source dates and additional notes

Source revision: 2018; historical letter and author correction
Retrieved: 2026-09-05

Drug-level caution

The handbook's GFR-based 2.5 mg twice-daily AF rows differ from the U.S. label's combined age, weight and serum-creatinine criteria. Dialysis evidence is limited. No combined algorithm has been generated.

No difference note is recorded here. This does not certify agreement.

Compare before choosing

Keep each source's dose, interval, renal measurement, indication, route and dialysis assumptions together. Do not construct a hybrid regimen from different sources.