Sodium Chloride 3%
Historical source. Current clinical review is incomplete. This monograph will be updated in the future.
Sodium Chloride 3% (opens in a new tab)Original source URL: https://globalrph.com/dilution/sodium-chloride/ | Retrieved 2026-11-04
Source dates, location and integrity
This historical article is separate from the reviewed claim cards. Product formulations and source dates may differ.
- Original source URL
- https://globalrph.com/dilution/sodium-chloride/ (opens in a new tab)
- Source date
- Not established in the retrieved source
- Retrieved
- 2026-11-04T19:50:44.691955+00:00
- Source location
- div.post-content
- Packaged content SHA-256
- cb712ee2fc849c9c91d6e127c448587ff620a9479a04d34b3cf59807b88919bf
- Original response SHA-256
- 14c2d2cf3841372d6507e1f62d73547a9ceea98d9b49655fcc9452b23944c6a3
- Source body SHA-256
- 841f71c2dd92dbc4b01003c0cb3ace3d25787ae8c7a5cd09a390fa6d8680e5fa
- This broader historical sodium chloride article is linked to the older sodium-chloride-3 catalog entry. It is not exact-product reconciliation for every concentration in the article.
Sodium Chloride 3% |
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Usual Diluents |
| -- |
Standard Dilutions [Amount of drug] [Infusion volume] [Infusion rate] |
| 513 meq/ 1000 ml (3%) See commentsCalculator or check out the custom calculator... |
Stability / Miscellaneous |
| Sodium (normal range): 136 to 147 meq/l.The goal of treatment is to get the patient out of immediate danger (return sodium level to > 120 meq/l). Usually reserved for severe symptomatic hyponatremia (level usually < 115). The maximum rate of increase (sodium level) is 2 meq/L/hr. The usual rate is 0.5 to 1 meq/L/hr-- these lower rates help avoid serious CNS complications (cerebral edema, pontine myelinolysis,seizures) and/or pulmonary edema.
Always verify the infusion rate and the length of infusion based on patient weight and sodium level. Calculation of the sodium deficit: Example: 70kg male. Na+= 110 meq/l Desired target= 125 meq/l. [0.6 x 70kg x (125-110)= 630 meq of Na+ needed]. Amount needed to increase serum sodium level by 1 meq/l/hr= 0.6 x 70kg x 1.0= 42 meq/hr (safe rate for this patient). 3%--hypertonic saline contains 513 meq/liter. Therefore: [desired rate per hr] / 513 x 1000 = infusion rate (ml/hr). Desired rate= 42/513 meq x 1000= 82 ml/hr Infusion time= [630 meq] / [42 meq/hr] = 15 hrs. Therefore: Infuse 3% saline at 82 ml/hr for 15 hours. Always verify the infusion rate and the length of infusion (using the calculations above) versus what is ordered. |