Search 237 product updates by drug, renal measure or dialysis term. Each result identifies the formulation, the label used and the limits of its renal guidance.
This summary uses the identified dated label. Verify the current label for this presentation before applying the regimen.
Renal measure
Creatinine clearance (CrCl), mL/min
Renal action or finding
Use the usual adult dose and interval at CrCl 60 mL/min or greater. Below that value use the table for the specified presentation and suspension concentration.
Limits and monitoring
Conventional hemodialysis and peritoneal dialysis remove little cefixime. Check the exact formulation when a reduced dose is needed.
Adult IV ceftaroline doses every 12 hours are 400 mg at CrCl above 30 through 50, 300 mg at 15 through 30, and 200 mg below 15 mL/min, including ESRD on HD. Administer after HD on dialysis days.
Limits and monitoring
The pediatric table uses a different renal metric. Confirm the patient's age, indication and infusion instructions.
This summary uses the identified dated label. Verify the current label for this presentation before applying the regimen.
Renal measure
Creatinine clearance (CrCl), mL/min
Renal action or finding
Reduce maintenance dosing for impaired renal elimination. Select dose and interval using the adult renal table, the infection severity, and the organism's susceptibility.
Limits and monitoring
Excess exposure may cause encephalopathy, myoclonus or seizures. Verify the relevant dialysis schedule separately.
For adults use the IV label's renal table when CrCl is below 50 mL/min. Select dose and interval for the indication and phase of treatment; use the HD instructions on dialysis days.
Limits and monitoring
Pediatric adjustments use indexed eGFR and age-specific criteria. Confirm ceftobiprole medocaril sodium versus active ceftobiprole when reading doses.
This summary uses the identified dated label. Verify the current label for this presentation before applying the regimen.
Renal measure
Serum creatinine, CrCl and urine protein
Renal action or finding
Do not initiate IV cidofovir if baseline serum creatinine exceeds 1.5 mg/dL, calculated CrCl is 55 mL/min or less, or urine protein is at least 100 mg/dL (2+).
Limits and monitoring
Systemic IV use requires labeled saline hydration and probenecid. Reassess creatinine and urine protein before each dose.
