Search 90 products by drug, renal measure or dialysis term. Each result identifies the formulation, the label used and the limits of its renal guidance.
This summary uses the identified dated label. Verify the current label for this presentation before applying the regimen.
Renal measure
Cockcroft-Gault creatinine clearance, mL/min
Renal action or finding
For PCI, the 0.75 mg/kg IV bolus is unchanged in renal impairment. Below CrCl 30 mL/min, lower the procedural infusion to 1 mg/kg/hour. In hemodialysis, use 0.25 mg/kg/hour.
Limits and monitoring
Check activated clotting time 5 minutes after the bolus and monitor anticoagulant status. Keep the indication and infusion concentration with the order.
At CrCl 15-29 mL/min, use the label's specified lower step: 180 mg becomes 90 mg daily, and 90 mg becomes 60 mg daily. At 30-89, no renal reduction is recommended.
Limits and monitoring
The supplied dose steps take precedence over a calculated percentage. Below 15 and dialysis are outside these bands.
For adults with eGFR 30 to <60, the usual renal maximum is 100 mg once daily. Below 30, initiation is not recommended. Adults already taking it who have albuminuria >300 mg/day may continue 100 mg daily for the labeled cardiorenal indication.
Limits and monitoring
Use the prescribing information's separate UGT-inducer instructions when applicable. This continuation exception does not transfer to canagliflozin/metformin.
Below eGFR 45, initiation is not recommended. At 45 to <60, the renal table caps canagliflozin at 100 mg/day. At 30 to <45, reassess continuation and use the same cap. Below 30, discontinue; use is contraindicated.
Limits and monitoring
These rules apply to a metformin-containing combination. Confirm the immediate-release formulation, interactions and contrast instructions.
Adult renal doses are total combination grams infused over 2 hours. CrCl 31-50: 1.25 g every 8 hours. At 16-30: 0.94 g every 12 hours. At 6-15: 0.94 g every 24 hours. At <=5: 0.94 g every 48 hours.
Limits and monitoring
Give after hemodialysis on HD days. Reassess CrCl at least daily when it is changing. Pediatric eGFR bands have a separate table.
The FDA label uses a 2-hour infusion. UCSF reports 3 hours and a separate institutional dialysis schedule. Select a complete source before using a dose.
DailyMed SPL version 25, effective 2025-04-30; posted Aug 11, 2026 | Selected sections checked 2026-11-07. Independent clinical review pending.
This summary uses the identified dated label. Verify the current label for this presentation before applying the regimen.
Renal measure
Creatinine clearance (CrCl), mL/min; use the product-specific calculation
Renal action or finding
For adult CrCl <30 mL/min, use 4 mg/kg IV every 48 hours for complicated skin/skin-structure infection or 6 mg/kg every 48 hours for S. aureus bloodstream infection. The interval is every 24 hours at CrCl >=30.
Limits and monitoring
The 48-hour schedule includes HD and CAPD. On HD days, dose after dialysis when possible. Check renal function and CPK more often than weekly in renal impairment.
The labeled adult doses for cSSSI and S. aureus bacteremia differ from UCSF institutional high-dose regimens. Check infection, weight convention and dialysis modality.
