GlobalRPh RX List - RECLAST
- Product / population
- RECLAST non-oncology zoledronic acid product; not the ZOMETA renal table.
- Renal measure
- Cockcroft-Gault CrCl, mL/min, using actual body weight; acute renal impairment is a separate contraindication.
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Renal dosing, restrictions and evidence limits
RECLAST is contraindicated at CrCl below 35 mL/min or with acute renal impairment. At CrCl at least 35, the source does not support a renal dose reduction. Calculate Cockcroft-Gault clearance using actual body weight before each dose. A dose must not exceed 5 mg and infusion must last at least 15 minutes. Withhold during suspected dehydration until volume status is normal and monitor at-risk patients. RECLAST and ZOMETA contain the same active ingredient but have different indications and renal instructions; do not use them together.