GlobalRPh Renal Dosing Masterv6.6
Evidence addition

Umeclidinium (INCRUSE ELLIPTA)

Local RX List renal extractBase record retrieved 2026-09-07See the evidence for this drug1 sources available - open source summaries, references and comparisons

Incruse Ellipta

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Rxlist source

GlobalRPh RX List - Incruse Ellipta

Product / population
Adult inhaled INCRUSE ELLIPTA 62.5 mcg; not combination inhalers.
Renal measure
CrCl in mL/min in the severe-impairment study

RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.

Renal dosing, restrictions and evidence limits

The source recommends one inhalation of umeclidinium 62.5 mcg once daily for COPD maintenance and explicitly requires no renal dose adjustment. Severe impairment, defined in its study as CrCl below 30 mL/min, did not meaningfully increase measured exposure. This product-specific statement is not evidence that other inhaled antimuscarinic combinations have identical renal restrictions. The selected passage does not give a separate dialysis supplemental-dose schedule.

Source revision: Source revision date not established in selected retrieval. | Retrieved: 2026-09-07. Retrieval date is not the revision date.

Source: https://globalrph.com/rx-list/incruse-ellipta-drug/

Scope: Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph. GlobalRPh v6.6.

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Evidence sources and renal implications

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GlobalRPh RX List

GlobalRPh RX List - Incruse Ellipta

Qualified no-adjustment statement. Apply only to the population, product and renal range described in this source.

Adult inhaled INCRUSE ELLIPTA 62.5 mcg; not combination inhalers.

Renal method: CrCl in mL/min in the severe-impairment study
Retrieved: 2026-09-07

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Source presence is not independent validation. A label mirror is not a second independent source; review the original reference and exact formulation.

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Renal dosing and precautions

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New source summary - independent clinical review pending. Summaries of the identified label sections are included locally. Source import and numeric transcription checks are not independent two-reference validation. Do not treat this card as an approved institutional dosing protocol.

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Original content / product scopeGlobalRPh RX List - Incruse Ellipta
Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://globalrph.com/rx-list/incruse-ellipta-drug/

Exact product and population

Adult inhaled INCRUSE ELLIPTA 62.5 mcg; not combination inhalers.

RDM36-SCOPE-umeclidinium-incruse · Source section: Selected source product scopeRenal section finder
Locally imported selected renal sections

GlobalRPh RX List renal information

Rxlist

GlobalRPh RX List - Incruse Ellipta

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GlobalRPh-hosted RX List · Adult inhaled INCRUSE ELLIPTA 62.5 mcg; not combination inhalers.

Renal method: CrCl in mL/min in the severe-impairment study
Source date: Source revision date not established in selected retrieval.
Retrieved: 2026-09-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Qualified no-adjustment statement. Apply only to the population, product and renal range described in this source.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

The source recommends one inhalation of umeclidinium 62.5 mcg once daily for COPD maintenance and explicitly requires no renal dose adjustment. Severe impairment, defined in its study as CrCl below 30 mL/min, did not meaningfully increase measured exposure. This product-specific statement is not evidence that other inhaled antimuscarinic combinations have identical renal restrictions. The selected passage does not give a separate dialysis supplemental-dose schedule.

RDM36-rxlist-umeclidinium-incruse-4daad6d1a2-C1 · Source locator: Dosage; renal impairment; pharmacokinetics.

Source identity and provenance
Source family
product_label_mirror
Source
https://globalrph.com/rx-list/incruse-ellipta-drug/
Retrieved
2026-09-07
Renal-function method
CrCl in mL/min in the severe-impairment study
Source date/version
Source revision date not established in selected retrieval.
Hash meaning
SHA-256 of local authored summary only; not original HTML, PDF or SPL bytes.
Local summary SHA-256
2c8604f4cdbf0c356ef5965251744834f7e5d89c4cba86d6bae2b46fe217107e

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://globalrph.com/rx-list/incruse-ellipta-drug/
Source retrieval
2026-09-07. This is not the source publication or label revision date.
Original source type
rxlist summary
Local text SHA-256
a561ed2d4b7dca819c5950b82818325058add7be806cb463b84956bc1918f5a2
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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