GlobalRPh RX List - THAM
- Product / population
- THAM tromethamine injection for acid-base correction; not a general renal-dose reduction algorithm.
- Renal measure
- Urine output, uremia and electrolyte/acid-base monitoring
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Selected sections only. Source mirror and underlying label are not independent confirmations.
Renal dosing, restrictions and evidence limits
The source contraindicates THAM in uremia and anuria. In renal disease or reduced urinary output, decreased elimination and hyperkalemia are concerns; use extreme caution, electrocardiographic monitoring and frequent serum potassium checks. Monitor glucose during and after therapy because prolonged hypoglycemia can follow excessive or rapid administration.
The source gives qualitative renal restrictions, not a validated CrCl-based adjustment table. Do not convert uremia, anuria or reduced urine output into an invented numerical cutoff or a dialysis dosing schedule.