Topotecan injection - HYCAMTIN | GlobalRPh Renal Dosing Master

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HYCAMTIN capsules and IV injection have different renal schedules

The selected IV renal table is single-agent guidance. The oral label uses different starting amounts and renal bands for its relapsed-SCLC indication. Both specify ideal body weight for Cockcroft-Gault.

Before applying: Confirm route and indication before selecting a band. Oral and IV doses cannot be interchanged mg for mg, and the IV single-agent table is not the cervical-cancer combination schedule.

Also check: HYCAMTIN capsules and IV injection have different renal schedules

Rxlist source

GlobalRPh RX List - HYCAMTIN IV

Product / population: Adults; single-agent IV HYCAMTIN; not oral capsules or cisplatin combination dosing
Renal measure: Cockcroft-Gault CrCl, mL/min, using ideal body weight

RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.

Renal dosing, restrictions and evidence limits

Single-agent adult ovarian cancer or small cell lung cancer: the usual dose is 1.5 mg/m2 IV over 30 minutes daily for five consecutive days, beginning a 21-day cycle. At CrCl 20-39 mL/min, reduce to 0.75 mg/m2/day. Use Cockcroft-Gault with ideal body weight. No adjustment is specified at >=40; data below 20 are insufficient for a recommendation.

This renal instruction is for single-agent IV treatment. It must not be transferred to oral topotecan or the separate cisplatin-containing cervical cancer schedule. Blood-count recovery requirements and toxicity modifications remain mandatory; this extract is not a complete chemotherapy order.

Source revision: September 2018 | Retrieved: 2026-09-07. Retrieval date is not the revision date.

Source: https://globalrph.com/rx-list/hycamtin-drug/

Scope: Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph. GlobalRPh v6.6.

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GlobalRPh RX List

GlobalRPh RX List - HYCAMTIN IV

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Adults; single-agent IV HYCAMTIN; not oral capsules or cisplatin combination dosing

Renal method: Cockcroft-Gault CrCl, mL/min, using ideal body weight
Retrieved: 2026-09-07

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route and indication

HYCAMTIN capsules and IV injection have different renal schedules

How to use this: Confirm route and indication before selecting a band. Oral and IV doses cannot be interchanged mg for mg, and the IV single-agent table is not the cervical-cancer combination schedule.

GlobalRPh RX List - HYCAMTIN IV Topotecan capsules - HYCAMTIN

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Renal dosing and precautions

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Rxlist source

GlobalRPh RX List - HYCAMTIN IV

Adults; single-agent IV HYCAMTIN; not oral capsules or cisplatin combination dosing

Method: Cockcroft-Gault CrCl, mL/min, using ideal body weight

Renal dosing, restrictions and evidence limits Read this complete source summary

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Original content / product scope GlobalRPh RX List - HYCAMTIN IV

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Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://globalrph.com/rx-list/hycamtin-drug/

Exact product and population

Adults; single-agent IV HYCAMTIN; not oral capsules or cisplatin combination dosing

RDM38-SCOPE-topotecan-hycamtin-iv · Source section: Selected source product scopeRenal section finder

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GlobalRPh RX List - HYCAMTIN IV

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GlobalRPh-hosted RX List · Adults; single-agent IV HYCAMTIN; not oral capsules or cisplatin combination dosing

Renal method: Cockcroft-Gault CrCl, mL/min, using ideal body weight
Source date: September 2018
Retrieved: 2026-09-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

RDM38-rxlist-topotecan-hycamtin-iv-771d00ff3d-C1 · Source locator: Dosage: recommended regimens and renal modification; renal impairment

Source identity and provenance

Source family: product_label_mirror
Source: https://globalrph.com/rx-list/hycamtin-drug/
Retrieved: 2026-09-07
Renal-function method: Cockcroft-Gault CrCl, mL/min, using ideal body weight
Source date/version: September 2018
Hash meaning: SHA-256 of local authored summary only; not original HTML, PDF or SPL bytes.
Local summary SHA-256: 8516c7e0229c64766ee45b245adfc8c08d1b994ff73869e5110fb9bb73198975

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source: https://globalrph.com/rx-list/hycamtin-drug/
Source retrieval: 2026-09-07. This is not the source publication or label revision date.
Original source type: rxlist summary
Local text SHA-256: 0f371827cc786add1d74e0e3d06a169ffa18542f5c393934a5fb57de14640566
Import versus clinical validation: Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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