Detrol LA - labeled renal guidance
Renal action and limits
Tolterodine (Detrol LA), adult extended-release oral capsules
Creatinine clearance (CrCl), mL/min; use the product-specific calculation
This summary uses the identified dated label. Verify the current label for this presentation before applying the regimen.
- Action or finding
- At CrCl 10-30 mL/min, use 2 mg once daily. Below 10 mL/min, use is not recommended because this population was not studied.
- Limits and monitoring
- Confirm the LA capsule and check CYP3A4 inhibitors. Immediate-release tablets have a different schedule.
- Before use
- Verify the current prescribing information for this presentation.
- Product / population
- Tolterodine (Detrol LA), adult extended-release oral capsules
- Renal measure
- Creatinine clearance (CrCl), mL/min; use the product-specific calculation
- Source revision
- DailyMed SPL version 1, effective 2017-03-23; posted Apr 11, 2017
- Retrieved
- 2026-11-07 (not the revision date)
Renal guidance: 2 and 8, renal impairment
At CrCl 10-30 mL/min, use 2 mg once daily. Below 10 mL/min, use is not recommended because this population was not studied. Confirm the LA capsule and check CYP3A4 inhibitors. Immediate-release tablets have a different schedule.
Source: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=88df13b1-090d-4894-a60a-878b370409c0
