GlobalRPh RX List - INNOHEP
- Product / population
- Subcutaneous tinzaparin; historical source renal/older-adult warning. Current U.S. availability not confirmed.
- Renal measure
- Age-dependent estimated CrCl in mL/min in the cited trial.
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Renal dosing, restrictions and evidence limits
The source warns of higher mortality than unfractionated heparin in an older renal-impaired study population: age at least 70 with CrCl 30 or less, or age at least 75 with CrCl 60 or less. It advises considering alternatives in older patients with renal insufficiency. No validated reduced-dose rescue strategy follows from that warning. Tinzaparin units are not interchangeable with those of other heparins.