GlobalRPh RX List - Widaplik
- Product / population
- Adult product-specific renal information; not a complete prescribing regimen.
- Renal measure
- GFR, mL/min, for the aliskiren interaction; otherwise qualitative monitoring.
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Renal dosing, restrictions and evidence limits
Monitor renal function periodically and adjust treatment if renal function deteriorates. RAAS inhibition and diuresis can cause oliguria or acute renal failure; monitor electrolytes and glucose as well. Avoid aliskiren coadministration in renal impairment with GFR below 60 mL/min. Telmisartan and amlodipine exposure findings do not establish a renal dose for the entire combination: renal effects on indapamide pharmacokinetics are unknown in this source.