GlobalRPh RX List - Gattex
- Product / population
- GATTEX subcutaneous dosing in adults and pediatric patients at least one year old with short-bowel syndrome.
- Renal measure
- Indexed eGFR (mL/min/1.73 m2) in the dosing recommendation; renal PK study separately uses CrCl.
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Renal dosing, restrictions and evidence limits
For moderate or severe impairment and end-stage renal disease, defined in the dosing section as eGFR below 60, use 0.025 mg/kg subcutaneously once daily. Do not replace the indexed-eGFR dosing criterion with the separate creatinine-clearance metric used in the pharmacokinetic study without reconciliation. This selected renal recommendation does not replace the full short-bowel management, safety surveillance, nutritional-support and dose-preparation instructions. Infant dosing is not supplied by this extract.