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Official source
Alyq - labeled renal guidance
Renal action and limits
Tadalafil (Alyq), adult oral tablets for pulmonary arterial hypertension Creatinine clearance (CrCl), mL/min; use the product-specific calculation
Action or finding
At CrCl 31-80 mL/min, start at 20 mg once daily and consider 40 mg once daily if tolerated. Avoid use in severe impairment or on hemodialysis.
Limits and monitoring
The renal table lists moderate impairment as 31-50 and severe as below 30. At exactly 30, verify the intended band with the prescribing team.
Before use
The cited PAH table does not assign exactly 30 mL/min to either adjacent band. Keep this boundary open and verify with the prescribing team.
DailyMed SPL version 6, effective 2023-04-01; posted Aug 20, 2026 | Selected sections checked 2026-11-07. Independent clinical review pending.
Tadalafil (Alyq), adult oral tablets for pulmonary arterial hypertension
Renal measure
Creatinine clearance (CrCl), mL/min; use the product-specific calculation
Source revision
DailyMed SPL version 6, effective 2023-04-01; posted Aug 20, 2026
Retrieved
2026-11-07 (not the revision date)
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
Renal guidance: 2.2 and 8.6
At CrCl 31-80 mL/min, start at 20 mg once daily and consider 40 mg once daily if tolerated. Avoid use in severe impairment or on hemodialysis. The renal table lists moderate impairment as 31-50 and severe as below 30. At exactly 30, verify the intended band with the prescribing team.
Source revision: DailyMed SPL version 6, effective 2023-04-01; posted Aug 20, 2026 | Retrieved: 2026-11-07. Retrieval date is not the revision date.
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Renal-context checklist: population, kidney trend and dialysis
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Source scope / renal recommendation differences
Alyq - product and source limitations
The cited PAH table does not assign exactly 30 mL/min to either adjacent band. Keep this boundary open and verify with the prescribing team.
How to use this: The cited PAH table does not assign exactly 30 mL/min to either adjacent band. Keep this boundary open and verify with the prescribing team.
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Official source
Alyq - labeled renal guidance
Tadalafil (Alyq), adult oral tablets for pulmonary arterial hypertension
Method: Creatinine clearance (CrCl), mL/min; use the product-specific calculation
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Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
At CrCl 31-80 mL/min, start at 20 mg once daily and consider 40 mg once daily if tolerated. Avoid use in severe impairment or on hemodialysis. The renal table lists moderate impairment as 31-50 and severe as below 30. At exactly 30, verify the intended band with the prescribing team.
RDM73-alyq-official-1 · Source locator: Renal guidance: 2.2 and 8.6
GlobalRPh RX List / product-label mirror · Tadalafil (Alyq), adult oral tablets for pulmonary arterial hypertension
Renal method: Use the renal measure explicitly present in the RX passage. Source date: Mirror revision not established in the reviewed passage. Retrieved: 2026-11-07
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Additional summaries stored on this page: 1 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.
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This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.
