GlobalRPh RX List - LOKELMA
- Product / population
- Sodium zirconium cyclosilicate - LOKELMA oral suspension; selected renal passages, not a complete prescribing monograph.
- Renal measure
- Chronic hemodialysis status and serum potassium; not a CrCl-based reduction.
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Renal dosing, restrictions and evidence limits
For chronic hemodialysis, give only on nondialysis days: start 5 g once daily; consider 10 g if potassium exceeds 6.5 mEq/L. Adjust using predialysis potassium after the long interdialytic interval; reassess potassium one week after initiation or adjustment. Maintenance is 5-15 g once daily on nondialysis days; reduce/stop for low potassium. This is not emergency treatment for life-threatening hyperkalemia. Separate other oral medicines by at least two hours in general, and monitor edema/volume status. Do not substitute the separate nondialysis correction regimen for the HD schedule.