Sitagliptin / simvastatin (JUVISYNC, historical source)

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Rxlist source

GlobalRPh RX List - JUVISYNC

Product / population: Historical JUVISYNC fixed sitagliptin/simvastatin tablets; current availability and exact label require confirmation.
Renal measure: Cockcroft-Gault creatinine clearance, mL/min.

RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.

Historical-source context. Do not replace current single-agent thresholds with these older combination bands.

Renal dosing, restrictions and evidence limits

This older fixed-combination source uses Cockcroft-Gault CrCl, not the indexed eGFR bands printed in newer single-agent JANUVIA material. At CrCl 30 to below 50 mL/min, it lists a starting combination of sitagliptin 50 mg/simvastatin 40 mg once each evening; patients already using simvastatin may retain the appropriate existing simvastatin strength with sitagliptin 50 mg. At CrCl at least 50, it specifies no sitagliptin renal reduction. Below 30 or with ESRD, the product is not recommended because appropriate combination strengths are unavailable. The simvastatin interaction limits still apply. This historical source is not confirmation of current U.S. availability or a recommendation to start the combination.

Source revision: Source revision date not established in selected retrieval. | Retrieved: 2026-09-07. Retrieval date is not the revision date.

Source: https://globalrph.com/rx-list/juvisync-drug/

Scope: Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph. GlobalRPh v6.6.

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GlobalRPh RX List

GlobalRPh RX List - JUVISYNC

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Historical JUVISYNC fixed sitagliptin/simvastatin tablets; current availability and exact label require confirmation.

Renal method: Cockcroft-Gault creatinine clearance, mL/min.
Retrieved: 2026-09-07

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Rxlist source

GlobalRPh RX List - JUVISYNC

Historical JUVISYNC fixed sitagliptin/simvastatin tablets; current availability and exact label require confirmation.

Method: Cockcroft-Gault creatinine clearance, mL/min.

Renal dosing, restrictions and evidence limits Read this complete source summary

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Original content / product scope GlobalRPh RX List - JUVISYNC

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Product identity selected for the separately displayed source protocols below. Reference: https://globalrph.com/rx-list/juvisync-drug/

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Historical JUVISYNC fixed sitagliptin/simvastatin tablets; current availability and exact label require confirmation.

RDM36-SCOPE-sitagliptin-simvastatin-juvisync · Source section: Selected source product scopeRenal section finder

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GlobalRPh RX List renal information

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GlobalRPh RX List - JUVISYNC

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GlobalRPh-hosted RX List · Historical JUVISYNC fixed sitagliptin/simvastatin tablets; current availability and exact label require confirmation.

Renal method: Cockcroft-Gault creatinine clearance, mL/min.
Source date: Source revision date not established in selected retrieval.
Retrieved: 2026-09-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

RDM36-rxlist-sitagliptin-simvastatin-juvisync-5baf1af7e6-C1 · Source locator: Dosage: Patients With Renal Impairment; concomitant-drug restrictions.

Source-specific limits

Historical-source context. Do not replace current single-agent thresholds with these older combination bands.

Source identity and provenance

Source family: product_label_mirror
Source: https://globalrph.com/rx-list/juvisync-drug/
Retrieved: 2026-09-07
Renal-function method: Cockcroft-Gault creatinine clearance, mL/min.
Source date/version: Source revision date not established in selected retrieval.
Hash meaning: SHA-256 of local authored summary only; not original HTML, PDF or SPL bytes.
Local summary SHA-256: ed1e763da8c399bb1114f78aa81acac8ecea99ac8bb23ae08d8a46a389d752fa

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source: https://globalrph.com/rx-list/juvisync-drug/
Source retrieval: 2026-09-07. This is not the source publication or label revision date.
Original source type: rxlist summary
Local text SHA-256: dc458d573cfe8097654352e1de943010da56bca87ad3eec0cf3854c2408ee183
Import versus clinical validation: Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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