GlobalRPh RX List - FYARRO
- Product / population
- FYARRO intravenous protein-bound sirolimus for its oncology indication; not oral transplant sirolimus.
- Renal measure
- CrCl, mL/min; estimating equation not established in the selected passage.
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Renal dosing, restrictions and evidence limits
No clinically significant pharmacokinetic difference was identified with mild or moderate impairment, CrCl 30 to 89. The effect of severe impairment is unknown. Do not use oral transplant-sirolimus doses or concentration targets to fill this intravenous product gap.