GlobalRPh Renal Dosing Masterv6.6
Evidence addition

Simvastatin tablets (ZOCOR)

Local RX List renal extractBase record retrieved 2026-09-07See the evidence for this drug1 sources available - open source summaries, references and comparisons

ZOCOR

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Rxlist source

GlobalRPh RX List - ZOCOR

Product / population
Single-agent oral simvastatin; selected starting dose, not combination-product guidance.
Renal measure
Creatinine clearance, mL/min.

RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.

Renal dosing, restrictions and evidence limits

For severe renal impairment defined here as CrCl 15-29 mL/min, start simvastatin 5 mg once daily. The source notes that ZOCOR 5 mg is no longer marketed and directs use of another simvastatin product for that dose. It supplies no specific reduction for mild/moderate impairment in this section and no regimen below 15 or on dialysis. Renal dosing does not remove the statin interaction and myopathy precautions.

Source revision: Source revision date not established in selected retrieval. | Retrieved: 2026-09-07. Retrieval date is not the revision date.

Source: https://globalrph.com/rx-list/zocor-drug/

Scope: Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph. GlobalRPh v6.6.

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Source-first renal review

Evidence sources and renal implications

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GlobalRPh RX List

GlobalRPh RX List - ZOCOR

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Single-agent oral simvastatin; selected starting dose, not combination-product guidance.

Renal method: Creatinine clearance, mL/min.
Retrieved: 2026-09-07

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Renal dosing and precautions

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New source summary - independent clinical review pending. Summaries of the identified label sections are included locally. Source import and numeric transcription checks are not independent two-reference validation. Do not treat this card as an approved institutional dosing protocol.

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Original content / product scopeGlobalRPh RX List - ZOCOR
Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://globalrph.com/rx-list/zocor-drug/

Exact product and population

Single-agent oral simvastatin; selected starting dose, not combination-product guidance.

RDM37-SCOPE-simvastatin-zocor · Source section: Selected source product scopeRenal section finder
Locally imported selected renal sections

GlobalRPh RX List renal information

Rxlist

GlobalRPh RX List - ZOCOR

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GlobalRPh-hosted RX List · Single-agent oral simvastatin; selected starting dose, not combination-product guidance.

Renal method: Creatinine clearance, mL/min.
Source date: Source revision date not established in selected retrieval.
Retrieved: 2026-09-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

For severe renal impairment defined here as CrCl 15-29 mL/min, start simvastatin 5 mg once daily. The source notes that ZOCOR 5 mg is no longer marketed and directs use of another simvastatin product for that dose. It supplies no specific reduction for mild/moderate impairment in this section and no regimen below 15 or on dialysis. Renal dosing does not remove the statin interaction and myopathy precautions.

RDM37-rxlist-simvastatin-zocor-dfabc0a94b-C1 · Source locator: Recommended Dosage in Patients With Renal Impairment.

Source identity and provenance
Source family
product_label_mirror
Source
https://globalrph.com/rx-list/zocor-drug/
Retrieved
2026-09-07
Renal-function method
Creatinine clearance, mL/min.
Source date/version
Source revision date not established in selected retrieval.
Hash meaning
SHA-256 of local authored summary only; not original HTML, PDF or SPL bytes.
Local summary SHA-256
e3536e0752602d52c55c6dddd5d7ffc557ad1f4fcd7b9145bf4dc456e7e500af

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://globalrph.com/rx-list/zocor-drug/
Source retrieval
2026-09-07. This is not the source publication or label revision date.
Original source type
rxlist summary
Local text SHA-256
067989541e6a2dc7e36ada8a57d240b40ec3f7c1532de0938c0398db24f5e659
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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