Before use: Sevelamer hydrochloride - RENAGEL tablets
Phosphorus concentration, meals and exact salt control these instructions. Carbonate and hydrochloride remain separate records; the adult switching instruction is not pediatric equivalence.
Before applying: Confirm the salt, formulation, phosphate concentration, current binder, GI history and interacting medicines. Do not treat these rows as dialysis-clearance replacement doses.
Confirm the product, indication and renal measure. The selected summary is not a complete prescribing monograph.
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Official source
Sevelamer hydrochloride - RENAGEL tablets
Product / population
Adults with CKD on dialysis; binder-naive initial dosing unless otherwise stated.
Renal measure
Serum phosphorus, mg/dL; not a creatinine-clearance dosing ladder.
Renal guidance and important limits
Limits that apply to these rows
Monitor bicarbonate and chloride. Bowel obstruction is contraindicated; review severe GI symptoms and medicine-binding interactions.
This is phosphorus-guided dosing in dialysis, not an eGFR reduction or a post-dialysis supplement. Nondialysis CKD safety and efficacy were not studied.
RENAGEL adult initial dosing - 800 mg tablets
Serum phosphorus (mg/dL)
Source-specific instruction
>5.5 and <7.5
One 800 mg tablet three times daily with meals
>=7.5 and <9.0
Two 800 mg tablets three times daily with meals
>=9.0
Two 800 mg tablets three times daily with meals
RENAGEL titration - source targets
Serum phosphorus (mg/dL)
Source-specific instruction
>5.5
Increase by one 800 mg tablet per meal at 2-week intervals
3.5-5.5
Maintain current dose
<3.5
Decrease by one 800 mg tablet per meal
Read the retained text before reformatting
RENAGEL adult initial dosing - 800 mg tablets
Serum phosphorus (mg/dL)
Source-specific instruction
>5.5 and <7.5
One 800 mg tablet three times daily with meals
>=7.5 and <9.0
Two 800 mg tablets three times daily with meals
>=9.0
Two 800 mg tablets three times daily with meals
RENAGEL titration - source targets
Serum phosphorus (mg/dL)
Source-specific instruction
>5.5
Increase by one 800 mg tablet per meal at 2-week intervals
3.5-5.5
Maintain current dose
<3.5
Decrease by one 800 mg tablet per meal
Monitor bicarbonate and chloride. Bowel obstruction is contraindicated; review severe GI symptoms and medicine-binding interactions.
This is phosphorus-guided dosing in dialysis, not an eGFR reduction or a post-dialysis supplement. Nondialysis CKD safety and efficacy were not studied.
Source revision: 12/2023 | Retrieved: 2026-09-10. Retrieval date is not the revision date.
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Evidence sources and renal implications
Choose a source to jump directly to its locally stored result. Qualitative precautions and evidence gaps remain visible even when no numerical clearance schedule is supplied.
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
Before using this finding
Confirm the salt, formulation, phosphate concentration, current binder, GI history and interacting medicines. Do not treat these rows as dialysis-clearance replacement doses.
Adults with CKD on dialysis; binder-naive initial dosing unless otherwise stated.
Renal method: Serum phosphorus, mg/dL; not a creatinine-clearance dosing ladder. Retrieved: 2026-09-10
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
Before using this finding
Confirm the salt, formulation, phosphate concentration, current binder, GI history and interacting medicines. Do not treat these rows as dialysis-clearance replacement doses.
Adults with CKD on dialysis; binder-naive initial dosing unless otherwise stated.
Renal method: Serum phosphorus, mg/dL; not a creatinine-clearance dosing ladder. Retrieved: 2026-09-10
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Renal-context checklist: population, kidney trend and dialysis
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These are specific issues found during source review, not an automated judgment that one source is universally correct. A label mirror and its original label are not independent evidence.
source scope and renal guidance
Before use: Sevelamer hydrochloride - RENAGEL tablets
Phosphorus concentration, meals and exact salt control these instructions. Carbonate and hydrochloride remain separate records; the adult switching instruction is not pediatric equivalence.
How to use this: Confirm the salt, formulation, phosphate concentration, current binder, GI history and interacting medicines. Do not treat these rows as dialysis-clearance replacement doses.
Choose a source, then jump to its renal or dialysis section. These links locate stored text; they do not merge regimens or certify that sources agree.
New source summary - independent clinical review pending. Summaries of the identified label sections are included locally. Source import and numeric transcription checks are not independent two-reference validation. Do not treat this card as an approved institutional dosing protocol.
Official source
Sevelamer hydrochloride - RENAGEL tablets
Adults with CKD on dialysis; binder-naive initial dosing unless otherwise stated.
Method: Serum phosphorus, mg/dL; not a creatinine-clearance dosing ladder.
No dialysis or renal heading shown? Read the complete source summary. Absence of a heading is not evidence that dose adjustment is unnecessary.
Compare or copy source versions
All content below is stored locally. Read a whole source version; do not combine its dose with another source's interval, renal metric or dialysis assumptions.
Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Sanofi / manufacturer prescribing information · Adults with CKD on dialysis; binder-naive initial dosing unless otherwise stated.
Renal method: Serum phosphorus, mg/dL; not a creatinine-clearance dosing ladder. Source date: 12/2023 Retrieved: 2026-09-10
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
Before using this finding
Confirm the salt, formulation, phosphate concentration, current binder, GI history and interacting medicines. Do not treat these rows as dialysis-clearance replacement doses.
Selected source sections stored locally. Not a complete monograph or independent clinical approval.
Renal guidance and important limits
Limits that apply to these rows
Monitor bicarbonate and chloride. Bowel obstruction is contraindicated; review severe GI symptoms and medicine-binding interactions.
This is phosphorus-guided dosing in dialysis, not an eGFR reduction or a post-dialysis supplement. Nondialysis CKD safety and efficacy were not studied.
RENAGEL adult initial dosing - 800 mg tablets
Serum phosphorus (mg/dL)
Source-specific instruction
>5.5 and <7.5
One 800 mg tablet three times daily with meals
>=7.5 and <9.0
Two 800 mg tablets three times daily with meals
>=9.0
Two 800 mg tablets three times daily with meals
RENAGEL titration - source targets
Serum phosphorus (mg/dL)
Source-specific instruction
>5.5
Increase by one 800 mg tablet per meal at 2-week intervals
3.5-5.5
Maintain current dose
<3.5
Decrease by one 800 mg tablet per meal
Read the retained text before reformatting
RENAGEL adult initial dosing - 800 mg tablets
Serum phosphorus (mg/dL)
Source-specific instruction
>5.5 and <7.5
One 800 mg tablet three times daily with meals
>=7.5 and <9.0
Two 800 mg tablets three times daily with meals
>=9.0
Two 800 mg tablets three times daily with meals
RENAGEL titration - source targets
Serum phosphorus (mg/dL)
Source-specific instruction
>5.5
Increase by one 800 mg tablet per meal at 2-week intervals
3.5-5.5
Maintain current dose
<3.5
Decrease by one 800 mg tablet per meal
Monitor bicarbonate and chloride. Bowel obstruction is contraindicated; review severe GI symptoms and medicine-binding interactions.
This is phosphorus-guided dosing in dialysis, not an eGFR reduction or a post-dialysis supplement. Nondialysis CKD safety and efficacy were not studied.
Monitor bicarbonate and chloride. Bowel obstruction is contraindicated; review severe GI symptoms and medicine-binding interactions.
This is phosphorus-guided dosing in dialysis, not an eGFR reduction or a post-dialysis supplement. Nondialysis CKD safety and efficacy were not studied.
GlobalRPh-hosted RX List · Adults with CKD on dialysis; binder-naive initial dosing unless otherwise stated.
Renal method: Serum phosphorus, mg/dL; not a creatinine-clearance dosing ladder. Source date: Revision not established in selected retrieval Retrieved: 2026-09-10
Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
Before using this finding
Confirm the salt, formulation, phosphate concentration, current binder, GI history and interacting medicines. Do not treat these rows as dialysis-clearance replacement doses.
Selected source sections stored locally. Not a complete monograph or independent clinical approval.
Renal guidance and important limits
Limits that apply to these rows
Monitor bicarbonate and chloride. Bowel obstruction is contraindicated; review severe GI symptoms and medicine-binding interactions.
This is phosphorus-guided dosing in dialysis, not an eGFR reduction or a post-dialysis supplement. Nondialysis CKD safety and efficacy were not studied.
RENAGEL adult initial dosing - 800 mg tablets
Serum phosphorus (mg/dL)
Source-specific instruction
>5.5 and <7.5
One 800 mg tablet three times daily with meals
>=7.5 and <9.0
Two 800 mg tablets three times daily with meals
>=9.0
Two 800 mg tablets three times daily with meals
RENAGEL titration - source targets
Serum phosphorus (mg/dL)
Source-specific instruction
>5.5
Increase by one 800 mg tablet per meal at 2-week intervals
3.5-5.5
Maintain current dose
<3.5
Decrease by one 800 mg tablet per meal
Read the retained text before reformatting
RENAGEL adult initial dosing - 800 mg tablets
Serum phosphorus (mg/dL)
Source-specific instruction
>5.5 and <7.5
One 800 mg tablet three times daily with meals
>=7.5 and <9.0
Two 800 mg tablets three times daily with meals
>=9.0
Two 800 mg tablets three times daily with meals
RENAGEL titration - source targets
Serum phosphorus (mg/dL)
Source-specific instruction
>5.5
Increase by one 800 mg tablet per meal at 2-week intervals
3.5-5.5
Maintain current dose
<3.5
Decrease by one 800 mg tablet per meal
Monitor bicarbonate and chloride. Bowel obstruction is contraindicated; review severe GI symptoms and medicine-binding interactions.
This is phosphorus-guided dosing in dialysis, not an eGFR reduction or a post-dialysis supplement. Nondialysis CKD safety and efficacy were not studied.
Monitor bicarbonate and chloride. Bowel obstruction is contraindicated; review severe GI symptoms and medicine-binding interactions.
This is phosphorus-guided dosing in dialysis, not an eGFR reduction or a post-dialysis supplement. Nondialysis CKD safety and efficacy were not studied.
Additional summaries stored on this page: 1 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.
This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.