Trizivir - labeled renal guidance
Renal action and limits
Abacavir sulfate, lamivudine, and zidovudine (Trizivir), oral tablet
Creatinine clearance (CrCl), mL/min
This summary uses the identified dated label. Verify the current label for this presentation before applying the regimen.
- Action or finding
- The fixed-dose tablet is not recommended at CrCl below 50 mL/min because its components cannot be adjusted independently.
- Limits and monitoring
- Use individually selected components if renal adjustment is necessary. Verify all active ingredients.
- Before use
- Verify the current prescribing information for this presentation.
- Product / population
- Abacavir sulfate, lamivudine, and zidovudine (Trizivir), oral tablet
- Renal measure
- Creatinine clearance (CrCl), mL/min
- Source revision
- DailyMed SPL version 2, posted Apr 28, 2014
- Retrieved
- 2026-11-07 (not the revision date)
Renal guidance: 8.6 Patients With Impaired Renal Function
The fixed-dose tablet is not recommended at CrCl below 50 mL/min because its components cannot be adjusted independently. Use individually selected components if renal adjustment is necessary. Verify all active ingredients.
Source: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3354e50f-4dc5-413f-b5ae-87353ab8913d
