GlobalRPh Renal Dosing Masterv7.4
Renal Dosing Master: fast drug lookup
Product-specific reference

Imipenem and cilastatin sodium (Primaxin I.V.), IV injection

Read renal action and limits

Primaxin I.V. / Imipenem and cilastatin sodium

READ THE SOURCE-SPECIFIC ANSWER

Renal guidance at a glance

Cautions / source differences (1)

Use the renal measure and units named by this source. Confirm product, indication, age, stable versus changing kidney function, and exact dialysis modality. The selected summary is not a complete prescribing monograph. Renal method and dosing checklist

Choose a source to read (2)

Display order is not a clinical ranking. Date of retrieval is not the label revision date. Sources are never merged into one regimen. Other sources and conflicts remain below.

1 additional source qualifications - review before use
Primaxin I.V. - product and source limitations

Use stable serum creatinine. The label restricts use below CrCl 15 unless hemodialysis is instituted within 48 hours. Confirm seizure risk and HD timing.

Before applying: Apply only to the stated formulation, indication and renal population.

Also check: Primaxin I.V. - product and source limitations

Rxlist source

Primaxin I.V. - selected RX renal passage

Choose a product and source Primaxin I.V. | Product label All evidence
Product / population
Imipenem and cilastatin sodium (Primaxin I.V.), IV injection
Renal measure
Use the renal measure explicitly present in the RX passage.
Source revision
Mirror revision not established in the reviewed passage.
Retrieved
2026-11-07 (not the revision date)

RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

This mirror and the underlying product label share a source family.

RX List: selected renal passage

The mirror requires a reduced adult regimen below CrCl 90 and specifies Cockcroft-Gault with stable renal function.

Source revision: Mirror revision not established in the reviewed passage. | Retrieved: 2026-11-07. Retrieval date is not the revision date.

Source: https://globalrph.com/rx-list/primaxin-iv-drug/

Scope: Selected renal passages reviewed; independent clinician adjudication pending. GlobalRPh v7.4.

Full source card / provenance

All sources, comparison tools and evidence navigation
Added / rechecked in v7.4

Read source findings

Read source-specific summaries and their qualifications. Retrieval date is not label revision date. Recent review does not imply clinical approval.

Official

Primaxin I.V. - labeled renal guidance

Retrieved: 2026-11-07
Source revision: DailyMed SPL version 35, posted Oct 23, 2026

Renal measure: Cockcroft-Gault CrCl, mL/min

Read this dated source finding
Rxlist

Primaxin I.V. - selected RX renal passage

Retrieved: 2026-11-07
Source revision: Mirror revision not established in the reviewed passage.

Renal measure: Use the renal measure explicitly present in the RX passage.

Read this dated source finding
See all retained evidence sources
Source-first renal review

Evidence sources and renal implications

Choose a source to jump directly to its locally stored result. Qualitative precautions and evidence gaps remain visible even when no numerical clearance schedule is supplied.

Read 1 source difference / applicability notes

GlobalRPh RX List

Primaxin I.V. - selected RX renal passage

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Imipenem and cilastatin sodium (Primaxin I.V.), IV injection

Renal method: Use the renal measure explicitly present in the RX passage.
Retrieved: 2026-11-07

Source presence is not independent validation. A label mirror is not a second independent source; review the original reference and exact formulation.

Product / population check

Confirm the exact formulation before using a renal source

These links compare product identities, not interchangeable doses. A selected summary is not a complete prescribing monograph.

Source-specific review points

Read the attributed comparison notes and source cards below. No conflict has been silently adjudicated.

Source-quality holds
Find text within this drug
Find a term without leaving this drug

Search the stored clinical text

Locate a word or phrase within this drug's source summaries. Choose all sources or one source to focus the search. The selection never hides warnings or source text, changes a dose, or proves that a renal finding is absent.

Find:

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All source summaries, original wording and provenance
Before applying a renal protocol

Check the setting. Compare whole sources.

No patient-specific dose is calculated. Context choices only display reminders; they do not validate, hide or change any regimen.

Share a reproducible source review

Choose sources below, then open a print-ready comparison with product scope, renal method, dates and cautions. Links can pin the exact local cards; they never contain patient values or choose a dose.

Open / share selected sources

Select two distinct source versions. The complete stored summaries will appear below.

Build a source-review outline for documentation

This creates a blank decision outline with the source identities you select, not a dose recommendation or completed clinical assessment. No patient fields are collected, saved or sent. Complete the clinical decisions in your approved documentation system.

Choose one or two sources above or use the source checkboxes below.

Renal-context checklist: population, kidney trend and dialysis

These prompts are a reading aid, not a prescription checklist or proof that all requirements have been met. No selections are stored or sent to a server.

Read the exact source scope, renal metric and date before selecting a row. No applicability assessment has been performed.

See source-specific renal methods and the clinical interpretation guide for the supporting context.

Read before choosing a regimen

Source differences and product cautions

Search differences across all drugs

These are specific issues found during source review, not an automated judgment that one source is universally correct. A label mirror and its original label are not independent evidence.

Source scope / renal recommendation differences

Primaxin I.V. - product and source limitations

Use stable serum creatinine. The label restricts use below CrCl 15 unless hemodialysis is instituted within 48 hours. Confirm seizure risk and HD timing.

How to use this: Apply only to the stated formulation, indication and renal population.

Selected renal passages reviewed; independent clinician adjudication pending.

Go directly to the relevant source section

Renal dosing and precautions

Choose a source, then jump to its renal or dialysis section. These links locate stored text; they do not merge regimens or certify that sources agree.

Independent clinical review is pending. These selected summaries are not an approved institutional dosing protocol. Confirm the exact product, the complete current source and local policy before use.

No dialysis or renal heading shown? Read the complete source summary. Absence of a heading is not evidence that dose adjustment is unnecessary.

Compare or copy source versions

All content below is stored locally. Read a whole source version; do not combine its dose with another source's interval, renal metric or dialysis assumptions.

Choose two source checkboxes below.
Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f41d8abd-7792-4918-1b93-bd83ea01955e

Product identity and scope

Imipenem and cilastatin sodium (Primaxin I.V.), IV injection

RDM74-primaxin-iv-identity-1 · Source section: Product identity and scopeRenal section finder
Separate U.S. product-label layer

FDA / DailyMed dosing and renal information

Official

Primaxin I.V. - labeled renal guidance

Open original reference

Open / share this exact local source

DailyMed / product prescribing information · Imipenem and cilastatin sodium (Primaxin I.V.), IV injection

Renal method: Cockcroft-Gault CrCl, mL/min
Source date: DailyMed SPL version 35, posted Oct 23, 2026
Retrieved: 2026-11-07

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Selected renal passages reviewed; independent clinician adjudication pending.

Renal guidance: 2.3 Dosage in Adult Patients with Renal Impairment / 8.6 Renal Impairment

Adult CrCl below 90 mL/min requires a lower imipenem/cilastatin IV regimen. Use the label's renal table and the row for the intended regimen and organism susceptibility. Use stable serum creatinine. The label restricts use below CrCl 15 unless hemodialysis is instituted within 48 hours. Confirm seizure risk and HD timing.

RDM74-primaxin-iv-official-1 · Source locator: Renal guidance: 2.3 Dosage in Adult Patients with Renal Impairment / 8.6 Renal Impairment

Source identity and provenance
Source family
product_label
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f41d8abd-7792-4918-1b93-bd83ea01955e
Retrieved
2026-11-07
Renal-function method
Cockcroft-Gault CrCl, mL/min
Source date/version
DailyMed SPL version 35, posted Oct 23, 2026
Hash meaning
SHA-256 of the local selected-source summary
Local summary SHA-256
218a1b454d6f3e13a8439d3891820f5d51da1a62d8565778499dc76860df897f
Locally imported selected renal sections

GlobalRPh RX List renal information

Rxlist

Primaxin I.V. - selected RX renal passage

Open original reference

Open / share this exact local source

GlobalRPh RX List / product-label mirror · Imipenem and cilastatin sodium (Primaxin I.V.), IV injection

Renal method: Use the renal measure explicitly present in the RX passage.
Source date: Mirror revision not established in the reviewed passage.
Retrieved: 2026-11-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Selected renal passages reviewed; independent clinician adjudication pending.

RX List: selected renal passage

The mirror requires a reduced adult regimen below CrCl 90 and specifies Cockcroft-Gault with stable renal function.

RDM74-primaxin-iv-rxlist-1 · Source locator: RX List: selected renal passage

Source-specific limits

This mirror and the underlying product label share a source family.

Source identity and provenance
Source family
product_label_mirror
Source
https://globalrph.com/rx-list/primaxin-iv-drug/
Retrieved
2026-11-07
Renal-function method
Use the renal measure explicitly present in the RX passage.
Source date/version
Mirror revision not established in the reviewed passage.
Hash meaning
SHA-256 of the local selected-source summary
Local summary SHA-256
26f82891d52e1b42ea262e5f4a814c55524e4c8a64b647ba77ded2c78c8d77d6

Provenance and preservation

Additional summaries stored on this page: 1 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f41d8abd-7792-4918-1b93-bd83ea01955e
Source retrieval
2026-11-07. This is not the source publication or label revision date.
Original source type
multisource addition
Local text SHA-256
6b205c1874448f58018443c56c61a09b0cf791ff10c2dee3dfc80899d61df5e8
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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