GlobalRPh Renal Dosing Masterv6.6
GlobalRPh source record

Risedronate (Actonel)

GlobalRPh source pageBase record retrieved 2026-09-05See the evidence for this drug1 sources available - open source summaries, references and comparisons
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Renal measure
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Historical source: not automatically current. Review current official labeling and separately attributed additions before use.

ACTONEL source regimens; do not transfer administration instructions to delayed-release risedronate.

Usual Dosing (Adults)

Postmenopausal osteoporosis treatment: 5 mg daily, 35 mg weekly, 75 mg on two consecutive days each month, or 150 mg monthly. Prevention: 5 mg daily or 35 mg weekly; the two monthly alternatives may also be considered. Men with osteoporosis: 35 mg weekly. Glucocorticoid-induced osteoporosis treatment/prevention: 5 mg daily. Paget disease: 30 mg daily for 2 months; after at least 2 months of observation, the same course may be repeated for relapse or failure to normalize alkaline phosphatase. More than one retreatment course was not studied in the source.

Renal Dosing

Not recommended with severe impairment, CrCl below 30 mL/min.

Hemodialysis

The source repeats the CrCl-below-30 restriction.

Source revision: Historical source; revision not established here | Retrieved: 2026-09-05. Retrieval date is not the revision date.

Source: https://globalrph.com/renal/risedronate/

Scope: Preserved historical source; no fresh clinical approval GlobalRPh v6.6.

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Preserved GlobalRPh source

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Renal method: Read the measure and population stated in the original source sections.
Retrieved: 2026-09-05

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Original content / product scope
Historical source content is not a current prescription. Original GlobalRPh recommendations are preserved, not automatically certified as current. Product-label and professional additions below are separately attributed. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.

Important source distinctions

ACTONEL source regimens; do not transfer administration instructions to delayed-release risedronate.

Locally stored source content

Original GlobalRPh protocol

Clinical facts and comments transcribed into a structured reading format. This is not a byte-for-byte HTML archive. Original source: https://globalrph.com/renal/risedronate/

Usual Dosing (Adults)

Postmenopausal osteoporosis treatment: 5 mg daily, 35 mg weekly, 75 mg on two consecutive days each month, or 150 mg monthly. Prevention: 5 mg daily or 35 mg weekly; the two monthly alternatives may also be considered. Men with osteoporosis: 35 mg weekly. Glucocorticoid-induced osteoporosis treatment/prevention: 5 mg daily. Paget disease: 30 mg daily for 2 months; after at least 2 months of observation, the same course may be repeated for relapse or failure to normalize alkaline phosphatase. More than one retreatment course was not studied in the source.

GRPH-risedronate-01 · Source section: Usual Dosing (Adults)Renal section finder

Renal Dosing

Not recommended with severe impairment, CrCl below 30 mL/min.

GRPH-risedronate-02 · Source section: Renal DosingRenal section finder

Hemodialysis

The source repeats the CrCl-below-30 restriction.

GRPH-risedronate-03 · Source section: HemodialysisRenal section finder

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 0 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://globalrph.com/renal/risedronate/
Source retrieval
2026-09-05. This is not the source publication or label revision date.
Original source type
globalrph individual
Local text SHA-256
fa5eb077c5cc5a01da065b874fbfad15389f721af2b5839e1a0ba1932c29d736
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

The original individual GlobalRPh pages commonly cite NIH/NLM DailyMed and instruct readers to review the applicable package insert for updates. That historical reference is preserved as context; it is not counted as an independently retrieved current label.

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