GlobalRPh Renal Dosing Masterv6.6
Evidence addition

Revefenacin inhalation solution (Yupelri)

Local official-label summaryBase record retrieved 2026-09-05See the evidence for this drug2 sources available - open source summaries, references and comparisons

Yupelri

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Official source

Revefenacin inhalation solution (Yupelri) - selected U.S. label sections

Product / population
YUPELRI inhalation solution by nebulization; not an oral product or an acute rescue regimen.
Renal measure
Qualitative degree of renal impairment; no renal cutoff invented.

Selected renal sections only, not a complete monograph. Exact product, indication, patient population, renal method and all other contraindications/interactions remain controlling.

Second independent renal reference and clinician adjudication remain pending; no all-indication, dialysis or pediatric dose may be inferred from an omitted field.

Renal dose and monitoring

Renal impairment does not require a dose adjustment. In severe renal impairment, monitor for systemic antimuscarinic adverse effects. A no-adjustment statement does not remove the need for monitoring.

Source revision: Revision not captured; retrieval date is not the revision date. | Retrieved: 2026-09-05. Retrieval date is not the revision date.

Source: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6dfebf04-7c90-436a-9b16-750d3c1ee0a6

Scope: Local label summary; independent clinical review pending. Not a two-source validated protocol. GlobalRPh v6.6.

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Evidence sources and renal implications

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Official product label

Revefenacin inhalation solution (Yupelri) - selected U.S. label sections

YUPELRI inhalation solution by nebulization; not an oral product or an acute rescue regimen.

Renal method: Qualitative degree of renal impairment; no renal cutoff invented.
Retrieved: 2026-09-05

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GlobalRPh RX List

GlobalRPh RX List - Yupelri

No adjustment within stated limits. This does not establish dosing outside the studied renal range or population.

Adult product-specific renal information; not a complete prescribing regimen.

Renal method: CrCl, mL/min, in the severe-impairment study.
Retrieved: 2026-09-07

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Renal dosing and precautions

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New source summary - independent clinical review pending. Summaries of the identified label sections are included locally. Source import and numeric transcription checks are not independent two-reference validation. Do not treat this card as an approved institutional dosing protocol.
Official source

Revefenacin inhalation solution (Yupelri) - selected U.S. label sections

YUPELRI inhalation solution by nebulization; not an oral product or an acute rescue regimen.

Method: Qualitative degree of renal impairment; no renal cutoff invented.

Renal dose and monitoringRead this complete source summary

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Original content / product scopeRevefenacin inhalation solution (Yupelri) - selected U.S. label sectionsGlobalRPh RX List - Yupelri
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Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6dfebf04-7c90-436a-9b16-750d3c1ee0a6

Product and population scope

YUPELRI inhalation solution by nebulization; not an oral product or an acute rescue regimen.

RDM32-revefenacin-yupelri-scope · Source section: Editorial scope for the selected U.S. labelRenal section finder
Separate U.S. product-label layer

FDA / DailyMed dosing and renal information

Official

Revefenacin inhalation solution (Yupelri) - selected U.S. label sections

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U.S. product labeling / DailyMed · YUPELRI inhalation solution by nebulization; not an oral product or an acute rescue regimen.

Renal method: Qualitative degree of renal impairment; no renal cutoff invented.
Source date: Revision not captured; retrieval date is not the revision date.
Retrieved: 2026-09-05

Local label summary; independent clinical review pending. Not a two-source validated protocol.

Renal dose and monitoring

Renal impairment does not require a dose adjustment. In severe renal impairment, monitor for systemic antimuscarinic adverse effects. A no-adjustment statement does not remove the need for monitoring.

RDM32-revefenacin-yupelri-1 · Source locator: 8.7

Source-specific limits

Selected renal sections only, not a complete monograph. Exact product, indication, patient population, renal method and all other contraindications/interactions remain controlling.

Second independent renal reference and clinician adjudication remain pending; no all-indication, dialysis or pediatric dose may be inferred from an omitted field.

Source identity and provenance
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6dfebf04-7c90-436a-9b16-750d3c1ee0a6
Retrieved
2026-09-05
DailyMed Set ID
6dfebf04-7c90-436a-9b16-750d3c1ee0a6
Renal-function method
Qualitative degree of renal impairment; no renal cutoff invented.
Source date/version
Revision not captured; retrieval date is not the revision date.
Hash meaning
SHA-256 identifies this local summary, not original SPL XML or a label PDF.
Local summary SHA-256
0a5e9df40b2fce4788cb82d9718b968dcf05fc4aa8721e790695514aff271cf1
Locally imported selected renal sections

GlobalRPh RX List renal information

Rxlist

GlobalRPh RX List - Yupelri

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GlobalRPh-hosted RX List · Adult product-specific renal information; not a complete prescribing regimen.

Renal method: CrCl, mL/min, in the severe-impairment study.
Source date: Source revision date not established in selected retrieval.
Retrieved: 2026-09-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
No adjustment within stated limits. This does not establish dosing outside the studied renal range or population.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

Renal impairment does not require a dose adjustment, but severe impairment warrants monitoring for systemic antimuscarinic effects. The source reports increased parent-drug and active-metabolite exposure at CrCl below 30 mL/min. End-stage renal disease was not evaluated. The no-adjustment statement must not be read as proof of dialysis-specific safety.

RDM34-rxlist-yupelri-drug-C1 · Source locator: Use in specific populations: renal impairment; clinical pharmacology: renal impairment.

Source identity and provenance
Source family
product_label_mirror
Source
https://globalrph.com/rx-list/yupelri-drug/
Retrieved
2026-09-07
Renal-function method
CrCl, mL/min, in the severe-impairment study.
Source date/version
Source revision date not established in selected retrieval.
Hash meaning
SHA-256 of local authored summary only, not original HTML, PDF or SPL bytes.
Local summary SHA-256
e9b4e0e28aa094f0329e6f5c681e5ca6c83bdaf9d309e81d2fb773c75620f349

Provenance and preservation

Additional summaries stored on this page: 1 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6dfebf04-7c90-436a-9b16-750d3c1ee0a6
Source retrieval
2026-09-05. This is not the source publication or label revision date.
Original source type
multisource addition
Local text SHA-256
481ae24c295de4324694dbc42093887bbe612f539f81eef023d2d5423b4b1556
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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