GlobalRPh RX List - Ultiva
- Product / population
- IV remifentanil administered by appropriately trained anesthesia clinicians.
- Renal measure
- CrCl in mL/min; ESRD PK study
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Renal dosing, restrictions and evidence limits
The source reports unchanged remifentanil pharmacokinetics in ESRD with creatinine clearance below 10 mL/min. Its carboxylic-acid metabolite lasts longer in anephric patients and is partly removed by hemodialysis. These are pharmacokinetic observations, not a complete renal anesthetic infusion protocol. Titrate within the indication-specific anesthesia regimen with continuous respiratory and hemodynamic supervision. The source has no data for ICU analgesic use longer than 16 hours. Do not infer a post-dialysis bolus or prolonged-ICU schedule from the metabolite findings.