Remdesivir (Veklury, adults) - selected U.S. labeling
- Product / population
- Adult COVID-19 treatment with intravenous remdesivir. Pediatric weight-based dosing is excluded.
- Renal measure
- All degrees of renal impairment; no renal dose reduction in selected labeling.
Labeled basic dosing
Give 200 mg IV on day 1, then 100 mg IV once daily from day 2. Infuse over 30-120 minutes. Course duration depends on hospitalization and disease severity.
Renal information and dialysis
The selected label recommends no change at any degree of renal impairment, including dialysis. Dosing need not be timed around dialysis.
Selected warnings and limits
Check hepatic laboratory tests and prothrombin time before treatment and as appropriate during therapy. Infusion reactions require access to emergency treatment.
Source: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c0978fa8-53ff-4ca2-82a7-567fd3e958ca