GlobalRPh Renal Dosing Masterv6.6
Evidence addition

Quizartinib tablets (VANFLYTA)

Local RX List renal extractBase record retrieved 2026-09-07See the evidence for this drug2 sources available - open source summaries, references and comparisons

VANFLYTA

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Renal guidance at a glance

Confirm the product, indication and renal measure. The selected summary is not a complete prescribing monograph.

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Display order is not a clinical ranking. Date of retrieval is not the label revision date. Sources are never merged into one regimen. Other sources and conflicts remain below.

Rxlist source

GlobalRPh RX List - Vanflyta

Product / population
VANFLYTA oral AML product; renal subsection only.
Renal measure
Cockcroft-Gault CrCl in mL/min.

RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.

Renal dosing, restrictions and evidence limits

No renal dose adjustment is recommended at CrCl 30-89. Severe impairment below 30 has not been studied, so no numerical reduced dose or dialysis schedule is derived. Preserve the indication, concomitant chemotherapy, QT-related precautions and interacting-drug instructions from the complete product information.

Source revision: Source revision date not established in selected retrieval. | Retrieved: 2026-09-07. Retrieval date is not the revision date.

Source: https://globalrph.com/rx-list/vanflyta-drug/

Scope: Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph. GlobalRPh v6.6.

Full source card / provenance

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Source-first renal review

Evidence sources and renal implications

Choose a source to jump directly to its locally stored result. Qualitative precautions and evidence gaps remain visible even when no numerical clearance schedule is supplied.

GlobalRPh RX List

GlobalRPh RX List - VANFLYTA

No adjustment within stated limits. This does not establish dosing outside the studied renal range or population.

Adult quizartinib tablets; renal restriction/evidence scope, not the full AML combination/maintenance regimen.

Renal method: Cockcroft-Gault creatinine clearance, mL/min.
Retrieved: 2026-09-07

Read local renal resultOpen original reference
GlobalRPh RX List

GlobalRPh RX List - Vanflyta

Qualified no-adjustment statement. Apply only to the population, product and renal range described in this source.

VANFLYTA oral AML product; renal subsection only.

Renal method: Cockcroft-Gault CrCl in mL/min.
Retrieved: 2026-09-07

Read local renal resultOpen original reference

Source presence is not independent validation. A label mirror is not a second independent source; review the original reference and exact formulation.

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All source summaries, original wording and provenance
Before applying a renal protocol

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No patient-specific dose is calculated. Context choices only display reminders; they do not validate, hide or change any regimen.

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Jump to renal guidanceClinician guide

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Build a source-review outline for documentation

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Renal-context checklist: population, kidney trend and dialysis

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Read the exact source scope, renal metric and date before selecting a row. No applicability assessment has been performed.

See source-specific renal methods and the clinical interpretation guide for the supporting context.

Go directly to the relevant source section

Renal dosing and precautions

Choose a source, then jump to its renal or dialysis section. These links locate stored text; they do not merge regimens or certify that sources agree.

New source summary - independent clinical review pending. Summaries of the identified label sections are included locally. Source import and numeric transcription checks are not independent two-reference validation. Do not treat this card as an approved institutional dosing protocol.

No dialysis or renal heading shown? Read the complete source summary. Absence of a heading is not evidence that dose adjustment is unnecessary.

Compare or copy source versions

All content below is stored locally. Read a whole source version; do not combine its dose with another source's interval, renal metric or dialysis assumptions.

Original content / product scopeGlobalRPh RX List - VANFLYTAGlobalRPh RX List - Vanflyta
Choose two source checkboxes below.
Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://globalrph.com/rx-list/vanflyta-drug/

Exact product and population

Adult quizartinib tablets; renal restriction/evidence scope, not the full AML combination/maintenance regimen.

RDM35-SCOPE-quizartinib-vanflyta · Source section: Selected source product scopeRenal section finder
Locally imported selected renal sections

GlobalRPh RX List renal information

Rxlist

GlobalRPh RX List - VANFLYTA

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GlobalRPh-hosted RX List · Adult quizartinib tablets; renal restriction/evidence scope, not the full AML combination/maintenance regimen.

Renal method: Cockcroft-Gault creatinine clearance, mL/min.
Source date: Source revision date not established in selected retrieval.
Retrieved: 2026-09-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
No adjustment within stated limits. This does not establish dosing outside the studied renal range or population.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

No renal dosage adjustment is recommended for Cockcroft-Gault CrCl 30 to 89 mL/min. Severe impairment below 30 mL/min was not studied. This does not establish a severe-impairment or dialysis regimen. QT and electrolyte-related contraindications, interaction adjustments and the oncology treatment-phase schedule must be checked independently.

RDM35-rxlist-quizartinib-vanflyta-aea541f329-C1 · Source locator: Use in Specific Populations: Renal Impairment; Contraindications; Clinical Pharmacology.

Source identity and provenance
Source family
product_label_mirror
Source
https://globalrph.com/rx-list/vanflyta-drug/
Retrieved
2026-09-07
Renal-function method
Cockcroft-Gault creatinine clearance, mL/min.
Source date/version
Source revision date not established in selected retrieval.
Hash meaning
SHA-256 of local authored summary only; not original HTML, PDF or SPL bytes.
Local summary SHA-256
e9f13ac548b85b09420ed512c6d4a64ea8d11ab8554348ee2849267ffae02dc2
Rxlist

GlobalRPh RX List - Vanflyta

Open original reference

Open / share this exact local source

GlobalRPh-hosted RX List · VANFLYTA oral AML product; renal subsection only.

Renal method: Cockcroft-Gault CrCl in mL/min.
Source date: Source revision date not established in selected retrieval.
Retrieved: 2026-09-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Qualified no-adjustment statement. Apply only to the population, product and renal range described in this source.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

No renal dose adjustment is recommended at CrCl 30-89. Severe impairment below 30 has not been studied, so no numerical reduced dose or dialysis schedule is derived. Preserve the indication, concomitant chemotherapy, QT-related precautions and interacting-drug instructions from the complete product information.

RDM40-rxlist-quizartinib-vanflyta-aea541f329-C1 · Source locator: Selected renal dosing, renal impairment, toxicity and pharmacokinetic subsections as identified in the summary.

Source identity and provenance
Source family
product_label_mirror
Source
https://globalrph.com/rx-list/vanflyta-drug/
Retrieved
2026-09-07
Renal-function method
Cockcroft-Gault CrCl in mL/min.
Source date/version
Source revision date not established in selected retrieval.
Hash meaning
SHA-256 of local authored summary only; not original HTML, PDF or SPL bytes.
Local summary SHA-256
cc56e9d42e0bea8ac7053ec211a05f1a3129af2a613f8492fb7a1c392c301355

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 2 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://globalrph.com/rx-list/vanflyta-drug/
Source retrieval
2026-09-07. This is not the source publication or label revision date.
Original source type
rxlist summary
Local text SHA-256
4426f83d267a69a913202b3a2cd7065277b9d40bc4eae054db62b1d4cd3a2aac
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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