GlobalRPh RX List - PRETOMANID
- Product / population
- Pretomanid - tablets in a combination tuberculosis regimen; selected renal passages, not a complete prescribing monograph.
- Renal measure
- Qualitative renal statement; no numerical renal-function threshold inferred.
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Renal dosing, restrictions and evidence limits
The effect of renal impairment on pretomanid safety, efficacy and pharmacokinetics is unknown. The source also states that the pretomanid/bedaquiline/linezolid combination has not established safety and effectiveness in renal impairment. This is an evidence gap, not a numerical dose reduction or proof of suitability. Each companion drug and the tuberculosis regimen requires its own review; no dialysis regimen is inferred.